{"id":371,"date":"2019-03-12T14:26:58","date_gmt":"2019-03-12T14:26:58","guid":{"rendered":"https:\/\/wp.uthscsa.edu\/dcsa\/?page_id=371"},"modified":"2025-03-20T14:49:59","modified_gmt":"2025-03-20T19:49:59","slug":"optical-imaging","status":"publish","type":"page","link":"https:\/\/lsom.uthscsa.edu\/dcsa\/research\/cores-facilities\/optical-imaging\/","title":{"rendered":"Optical Imaging Facility"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<\/p>\n<h3>Mission:<\/h3>\n<p>To make available state-of-the-art imaging technology to investigators on UT Health\u2019s campus and neighboring scientific community.<\/p>\n<h3>Rationale:<\/h3>\n<p><span style=\"font-weight: 400\">High-end instrumentation for acquisition and analysis of optical data is expensive and requires continued maintenance and improvements. The necessary commitment to this technology is often difficult to maintain within individual laboratories, especially when optical imaging is not a major focus for the laboratory. Therefore, the Core Optical Imaging Facility fills a critical need of UTHSA investigators and neighboring scientific community by offering,<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">access to state-of-the-art technology for imaging of living cells, tissues, and animals.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">consultation, education and assistance regarding the theory and application of optical imaging techniques.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">technical advice on specimen preparation techniques and probe selection.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">New developments in optical microscopy coupled with the vast array of bio-reagents available have made it possible to observe directly the dynamics of the molecular, chemical, structural and functional environment of cells at the cellular and sub-cellular level. In particular, fluorescence microscopy has become an essential tool for scientist to detect cellular components using antibodies, nucleic acid probes and fluorescent fusion proteins as markers and to observe physiological changes using fluorescent ion indicators.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Developments in optical microscopy coupled with the now vast array of bio-reagents available have made it possible to observe directly the dynamics of the molecular, chemical, structural and functional environment of cells at the sub-cellular level. In particular, fluorescence microscopy has become an essential tool for scientist to detect specific cellular components using antibodies, nucleic acid probes and fluorescent fusion proteins as markers and to observe physiological changes using fluorescent ion indicators.<\/span><\/p>\n<h3>Publication Acknowledgements<strong>:<\/strong><\/h3>\n<p><span style=\"font-weight: 400\">The facility should be listed in the &#8220;Acknowledgements&#8221; section of any publication using data generated in the OIF as follows:<\/span><\/p>\n<ul>\n<li>Images were generated in the Core Optical Imaging Facility which is supported by UT Health San Antonio and NIH-NCI P30 CA54174.<\/li>\n<li>Zeiss LSM 980 confocal with Airyscan2 users are required to include this additional acknowledgement: The Zeiss LSM confocal with Airyscan 2 was funded by NIH S10 grant 1S10OD036297-01.<\/li>\n<li>Zeiss Lightsheet 7 users need to include this additional acknowledgement: The Zeiss Lightsheet 7 microscope was funded by NIH S10 grant 1S10OD030383-01.<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243;] \n        <a class=\"panel no-equilizer panel-mobile text-center colorized\" href=\"https:\/\/lsom.uthscsa.edu\/dcsa\/research\/cores-facilities\/optical-imaging\/contact\/\" title=\"\" target=\"\">\n            <span class=\"circle close2x mid-icon\"><span><i class=\"fa fa-users\"><\/i><\/span><\/span><br>\n            <h3 >Optical Imaging Facility Contact Information<\/h3>\n            <p><\/p>\n        <\/a> \n        <a class=\"panel no-equilizer panel-mobile text-center colorized colorized-institutional\" href=\"https:\/\/lsom.uthscsa.edu\/dcsa\/research\/cores-facilities\/optical-imaging\/equipment\/\" title=\"\" target=\"\">\n            <span class=\"circle close2x mid-icon\"><span><i class=\"fa fa-thermometer-empty\"><\/i><\/span><\/span><br>\n            <h3 >Equipment<\/h3>\n            <p><\/p>\n        <\/a> \n        <a class=\"panel no-equilizer panel-mobile text-center colorized colorized-academics\" href=\"https:\/\/lsom.uthscsa.edu\/dcsa\/research\/cores-facilities\/optical-imaging\/fees\/\" title=\"\" target=\"\">\n            <span class=\"circle close2x mid-icon\"><span><i class=\"fa fa-money\"><\/i><\/span><\/span><br>\n            <h3 >Facility Fees<\/h3>\n            <p><\/p>\n        <\/a> \n        <a class=\"panel no-equilizer panel-mobile text-center colorized\" href=\"https:\/\/lsom.uthscsa.edu\/dcsa\/research\/cores-facilities\/optical-imaging\/rules\/\" title=\"\" target=\"\">\n            <span class=\"circle close2x mid-icon\"><span><i class=\"fa fa-info\"><\/i><\/span><\/span><br>\n            <h3 >Rules<\/h3>\n            <p><\/p>\n        <\/a>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text] Mission: To make available state-of-the-art imaging technology to investigators on UT Health\u2019s campus and neighboring scientific community. Rationale: High-end instrumentation for acquisition and analysis of optical data is expensive and requires continued maintenance and improvements. The necessary commitment to this technology is often difficult to maintain within individual laboratories, especially when optical imaging [&hellip;]<\/p>\n","protected":false},"author":159,"featured_media":0,"parent":334,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/child-page.php","meta":{"footnotes":""},"class_list":["post-371","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Optical Imaging Facility - Cell Systems and Anatomy<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lsom.uthscsa.edu\/dcsa\/research\/cores-facilities\/optical-imaging\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Optical Imaging Facility - Cell Systems and Anatomy\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text] Mission: To make available state-of-the-art imaging technology to investigators on UT Health\u2019s campus and neighboring scientific community. 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