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Grand Rounds: AAFP POEMs – Calibration and Discrimination of the Framingham Risk Score and the Pooled Cohort Equations

Event Details:

Overview:

Overshot Through the Heart: Calibration and discrimination of the Framingham Risk Score and the Pooled Cohort Equations. We increasingly rely on risk scores such as the Pooled Cohort Equation or the older Framingham Risk Score to make decisions about prescribing statins or aspirin. The Pooled Cohort Equation is recommended by current ACC/AHA guidelines because it is believed to better represent contemporary cardiovascular risk, which has been slowly declining since the Framingham Risk Score was first developed. Both the Framingham Risk Score and the Pooled Cohort Equations significantly overpredicted the five-year risk of a composite cardiovascular event outcome. This is consistent with other research and should give us pause as we use these risk scores to guide therapeutic decision-making. For example, a person with a 10-year risk of 10% probably has a true risk closer to 5%, leading to very different guideline recommendations for a statin.

Objectives:

• Assess the calibration and discrimination of the Framingham Risk Score and Pooled Cohort Equations in Ontario, Canada
• Appraise the validity of these risk scores in pre-specified subgroups to gain additional perspectives.
• Analyze the need for further refinement of cardiovascular disease risk prediction scores.

Financial Disclosures:

Melanie Perez Dones, MD, Alexis Ramos, MD and their faculty mentor Marissa Emadi, MD have no financial relationships with ineligible companies to disclose.

The Family & Community Medicine Professional Development and Grand Rounds Committee members (Maria Del Pilar Montañez Villacampa, MD, Stacy Ogbeide, PsyD, Yun Shi, MD, Mark Nadeau, MD, Marcy Wiemers, MD, Christine Song, DO, Nehman Andry, MD, Gabriela Gibson-Lopez, PsyD, Margaret Finley, MD, Richel Avery, MD, Lauren Fuller, MD, Jeff Svec, MD, Oralia Bazaldua, PharmD and Nichole Rubio) have no financial relationships with ineligible companies to disclose.

The Family & Community Medicine Professional Development and Grand Rounds Committee member Carlos Roberto Jaén, MD has disclosed he receives royalties from General Practice and Family Medicine for being UpToDate Editor-in-Chief.

AMA PRA Category 1 Credits™ (1.00 hours), Non-Physician Participation Credit (1.00 hours)

Target Audience:

Specialties – Primary Care; Family Medicine  
Faculty, residents, other health care providers and staff from our department; physicians and health care providers from San Antonio and South Texas; and medical students in our third-year clerkship and fourth year rotations. 

Accreditation:

The UT Health Science Center San Antonio is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation:

The UT Health Science Center San Antonio designates this live activity up to a maximum of 1.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nurses and other healthcare professionals will receive a Certificate of Attendance. For information on applicability and acceptance, please consult your professional licensing board.

For activity related questions, please contact:

Name: Nichole Rubio- FCM Grand Rounds Coordinator
Email: rubion@uthscsa.edu

For CME general questions, please contact:

Ph: (210) 567-4445
Email: cme@uthscsa.edu