Grand Rounds – DPP-4 Inhibitors And GLP-1 Agonists: The Perfect Pairing, Or Better Off Alone?

Event Date & Time

June 16, 2021 at 12:30pm - 1:30pm


Video Conference

Event Details:


Type 2 diabetes mellitus (T2DM) is one of the most common disease states encountered in primary care, affecting 10.6% of patients in Bexar County. The incretin agents, DPP-4 inhibitors and GLP-1 agonists, are used for the treatment of T2DM by promoting glucose-dependent insulin release by different mechanisms. The purpose of this presentation is to determine the safety and potential for synergy of dual incretin therapy by reviewing the available literature.


  1.   Describe the role of incretins in the pathophysiology of type 2 diabetes mellitus (T2DM)
  2.   Review the pharmacology and place in therapy for dipeptidyl peptidase 4 (DPP-4) inhibitors and glucagon-like peptide-1 (GLP-1) agonists
  3.   Formulate an evidence-based recommendation regarding the use of both incretin agents in the treatment of T2DM

Financial Disclosures:

Erica L. Torres, PharmD and her faculty mentor DeWayne Davidson, PharmD have no relevant financial relationships with commercial interests to disclose.

The Family & Community Medicine Professional Development and Grand Rounds Committee members (Mark Nadeau, MD, Marcy Wiemers, MD, Maria Del Pilar Montañez Villacampa, MD, Christine Song, DO, Nehman Andry, MD, Gabriela Lopez, PsyD, Maureen Alvarado, DO, Yun Shi, MD, Stacy Ogbeide, PsyD, Inez I. Cruz, PhD, and Nichole Rubio) have no relevant financial relationships to commercial interests to disclose.

The Family & Community Medicine Professional Development and Grand Rounds Committee member Carlos Roberto Jaén, MD has disclosed he receives royalties from General Practice and Family Medicine for being UpToDate Editor-in-Chief.

AMA PRA Category 1 Credits™ (1.00 hours), Non-Physician Participation Credit (1.00 hours)

Target Audience:

Specialties – Primary Care; Family Medicine  
Faculty, residents, other health care providers and staff from our department; physicians and health care providers from San Antonio and South Texas; and medical students in our third-year clerkship and fourth year rotations. 


The UT Health Long San Antonio School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation:

The Long School of Medicine designates this live activity up to a maximum of 1.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nurses and other healthcare professionals will receive a Certificate of Attendance. For information on applicability and acceptance, please consult your professional licensing board.

For activity related questions, please contact:

Name: Nichole Rubio- FCM Grand Rounds Coordinator


For CME general questions, please contact:

Ph: (210) 567-4445




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About the Speaker(s)

Erica Torres, PharmDErica L. Torres, PharmD
PGY2 Ambulatory Care Pharmacy Resident
Department of Pharmacotherapy & Pharmacy Services
University Health