{"id":3580,"date":"2025-02-25T14:50:51","date_gmt":"2025-02-25T20:50:51","guid":{"rendered":"https:\/\/lsom.uthscsa.edu\/nephrology\/?p=3580"},"modified":"2025-02-26T15:04:06","modified_gmt":"2025-02-26T21:04:06","slug":"new-publication-alert-on-the-kidney-brain-axis","status":"publish","type":"post","link":"https:\/\/lsom.uthscsa.edu\/nephrology\/2025\/02\/25\/new-publication-alert-on-the-kidney-brain-axis\/","title":{"rendered":"New publication alert on the Kidney-Brain axis!"},"content":{"rendered":"<p>Led by our PhD graduate, Dr. Afaf Saliba, under the mentorship of our director Dr. Kumar Sharma!<\/p>\n<p><a href=\"https:\/\/insight.jci.org\/articles\/view\/180229\" target=\"_blank\" rel=\"noopener\">https:\/\/insight.jci.org\/articles\/view\/180229<\/a><\/p>\n<p>This research highlights a crucial connection between kidney disease and brain health. The team found that quinolinic acid, a byproduct of tryptophan metabolism, builds up in the plasma kidney and brain during kidney failure, associated with inflammation and potential damage.<\/p>\n<p>These insights open new possibilities for better diagnosing and understanding of neurological complications in kidney disease.<\/p>\n<p>Congratulations to Dr. Saliba and the multidisciplinary teams for this valuable contribution!<\/p>\n<p>Authors: Afaf Saliba, Subrata Debnath, Ian Tamayo, Hak Joo Lee, NAGARJUNACHARY RAGI, Falguni Das, Richard Montellano, Jana Tumova, Meyer Maddox, Esmeralda Trevino, Pragya Singh, Ph.D., Caitlyn Fastenau, Soumya Maity, Guanshi Zhang, Leila Hejazi, Manjeri A. Venkatachalam, Jason C. O&#8217;Connor, Bernard Fongang, Sarah Hopp, Kevin F. Bieniek, Ph.D., Jim Lechleiter , Ph D., Kumar Sharma, MD<\/p>\n<p><a href=\"https:\/\/lsom.uthscsa.edu\/nephrology\/2025\/02\/25\/new-publication-alert-on-the-kidney-brain-axis\/180229-ins-rg-rv-4_ga_860192\/\" rel=\"attachment wp-att-3586\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-3586\" src=\"https:\/\/lsom.uthscsa.edu\/nephrology\/wp-content\/uploads\/sites\/38\/2025\/02\/180229-INS-RG-RV-4_ga_860192-550x385.jpg\" alt=\"\" width=\"550\" height=\"385\" srcset=\"https:\/\/lsom.uthscsa.edu\/nephrology\/wp-content\/uploads\/sites\/38\/2025\/02\/180229-INS-RG-RV-4_ga_860192-550x385.jpg 550w, https:\/\/lsom.uthscsa.edu\/nephrology\/wp-content\/uploads\/sites\/38\/2025\/02\/180229-INS-RG-RV-4_ga_860192-785x550.jpg 785w, https:\/\/lsom.uthscsa.edu\/nephrology\/wp-content\/uploads\/sites\/38\/2025\/02\/180229-INS-RG-RV-4_ga_860192-768x538.jpg 768w, https:\/\/lsom.uthscsa.edu\/nephrology\/wp-content\/uploads\/sites\/38\/2025\/02\/180229-INS-RG-RV-4_ga_860192-1536x1076.jpg 1536w, https:\/\/lsom.uthscsa.edu\/nephrology\/wp-content\/uploads\/sites\/38\/2025\/02\/180229-INS-RG-RV-4_ga_860192.jpg 1836w\" sizes=\"auto, (max-width: 550px) 100vw, 550px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Led by our PhD graduate, Dr. Afaf Saliba, under the mentorship of our director Dr. Kumar Sharma! https:\/\/insight.jci.org\/articles\/view\/180229 This research highlights a crucial connection between kidney disease and brain health. The team found that quinolinic acid, a byproduct of tryptophan metabolism, builds up in the plasma kidney and brain during kidney failure, associated with inflammation [&hellip;]<\/p>\n","protected":false},"author":391,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,1],"tags":[],"class_list":["post-3580","post","type-post","status-publish","format-standard","hentry","category-news","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>New publication alert on the Kidney-Brain axis! - Nephrology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lsom.uthscsa.edu\/nephrology\/2025\/02\/25\/new-publication-alert-on-the-kidney-brain-axis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New publication alert on the Kidney-Brain axis! - Nephrology\" \/>\n<meta property=\"og:description\" content=\"Led by our PhD graduate, Dr. Afaf Saliba, under the mentorship of our director Dr. Kumar Sharma! https:\/\/insight.jci.org\/articles\/view\/180229 This research highlights a crucial connection between kidney disease and brain health. 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