Dr. Rodriguez smiles for his staff photo.



Pavel Rodriguez, M.D., Ph.D.

Assistant Professor


08/2003 – 05/2007 BA Washington University in St. Louis
08/2007 – 05/2011 MD Duke University School of Medicine
08/2011 – 05/2017 PhD Univ. of Texas HSC San Antonio (Radiological Sciences)
July 2011 – June 2017 Internship and Diagnostic Radiology Residency, UT HSC San Antonio
July 2017 – June 2018 Diagnostic Neuroradiology Fellowship, Hospital of the University of
Pennsylvania, Philadelphia
July 2018 – June 2019 Interventional Neuroradiology Fellowship, Hospital of the University of
Pennsylvania, Philadelphia


Pilot Phase II Clinical Trial: Efficacy of Methylene Blue in Mild Cognitive Impairment
RSNA Research Resident Grant, 2016-2017, $30,000

Methylene blue enhancement of fMRI brain activity, memory and cognition in healthy aging and MCI, National Institutes of Health, National Institute of Aging
Loan Repayment Program, 2015-2017, $70,000

NIH/NCATS Institute for the Integration of Medicine and Science Phase II Clinical Trial: Methylene blue in healthy aging and Alzheimer’s disease patients
Co-Principal Investigator with Donald Royall, MD, 2015-2016, $50,000

R25 Administrative Supplement NIH: National Institute of Biomedical Imaging and Bioengineering (NIBIB), 2015-2016, $62,553

Methylene Blue enhancement of fMRI brain activity, memory and cognition in healthy Aging and MCI NIH: National Institute of Aging, Claude D. Pepper Center Grant Co-PI in project under umbrella grant, 2015-2016, $50,000

Multimodal MRI-based diagnosis and treatment of mild cognitive impairment
UT Brain Seed Grant, 2015-2017, $75,0000

Beneficial effects of methylene blue on human cognitive and fMRI measures Julio Palmaz Endowment Research Pilot Grant, 2013-2014, $3000

Neuroprotective effect of methylene blue in rodent permanent ischemia Julio Palmaz Endowment Research Pilot Grant, 2012-2013, $3000


American Society of Neuroradiology (Member, 01/2014 – Pres.)
American Society of Head and Neck Radiology (Member, 7/2011 – Pres.)
Radiological Society of North America (Member, 01/2011 – Pres.)
American College of Radiology (Member, 01/2011 – Pres.)
Association of University Radiologists (Member, 01/2011 – Pres.)
International Society for Magnetic Resonance in Medicine (Member, 11/2013 – Pres.)


Rodriguez, P., Eric L., Kurtz R. Anti-LGI1 Encephalitis – A Case Report of a Recently Described Disease
Entity. Neurographics. In Press May 2019

Jurkiewicz, M.T., Rodriguez, P., Walman, A.T., Pollock, A., Olfactory Bulb Hyperplasia in Alexander Disease.
Journal of Clinical and Diagnostic Research, 13(3): TD01-02, 2019

Rodriguez, P. Efficacy of Methylene Blue in Rodent Stroke and Human Cognitive Function (Doctoral
Dissertation).ProQuest Dissertation Publishing. Pub. ID 10264621, 2017.

Zhou W., Muir, E.R., Nagi, K.S., Chalfin, S., Rodriguez, P., Duong, T.Q. Retinotopic fMRI Reveals Visual
Dysfunction and Functional Reorganization in the Visual Cortex and Mild to Moderate Glaucoma Patients.
Journal of Glaucoma. 10.109/IJG.0000000000000641, 2016.

Rodriguez, P., Zhou, W., Barrett, D.W, Altmeyer, W.T., Gutierrez, J.E., Lancaster, J.L., Gonzalez-Lima, F.,
Duong, T.Q.: Multimodal Randomized fMRI Study of the Effects of Methylene Blue in the Human Brain.
Radiology 281 (2): 516-526, 2016.

Rodriguez, P., Singh, A.P., Malloy, K.E., Zhou, W, Barrett, D.W., Franklin, C.G., Altmeyer, W., Gutierrez,
J.E., Heyl, B.L., Lancaster, J.L., Gonzalez-Lima, F., Duong, T,Q.: Methylene Blue modulates functional
connectivity in the human brain. Brain Imaging and Behavior 10.1007/s11682-016-954-6: 1-9, 2016.

Rodriguez, P., Zhao, J., Milman, B., Duong, T.Q. Efficacy of combination normobaric oxygen and methylene
blue treatment in ischemic stroke. Brain and Behavior. 6 (7): e00478, 2016.

Tiwari, Y.V., Zhao, J., Sun, Y., Du, F., Rodriguez, P., Shen, Qiang., Duong, T.Q. Normobaric hyperoxia
treatment of experimental ischemic stroke: effects of stroke severity and treatment duration.
Brain Research 1635: 121-129, 2016.

Jiang, Z., Watts, L.T., Huang, S., Shen, Q., Rodriguez, P., Chen, C., Zhou, C., Duong, T.Q. The Effects of
Methylene Blue on Autophagy and Apoptosis in MRI defined Normal Tissue, Ischemic Penumbra and
Ischemic Core. PLoS One. 10(6): e0131929, 2015.

Rodriguez, P., Zhao, J., Shen, Q., Huang, S., Duong, T.Q. Methylene blue treatment delays progression of
perfusion-diffusion mismatch to infarct in permanent ischemic stroke.
Brain Research. 1588: 144-149, 2014.

Shen, Q., Fang, D., Huang, S., Rodriguez, P., Watts, L.T., Duong, T.Q. Neuroprotective efficacy of methylene
blue in ischemic stroke: a longitudinal MRI study.
PLoS One. 8(11) e79833: 1-5, 2013.

Hardman, R.L., Rahal, A., Walker, J., Tavakoli, S., Rodriguez, P., Vargas, D., Suri, R., Garcia-Rojas, X., Jung,
A.J., Fullerton, G.D., Clarke, G., Dodd, G.D.: Combined radiology residency-PhD program: 10-year review of program results.
Journal American College of Radiology. 10(10): 738-41, 2013.

Rishniw, M., Rodriguez, P., Que, J., Burke, Z.D., Tosh, D., Chen, H., Chen, X.: Molecular Aspects of
esophageal development. Annals of New York Academy of Science. 1232: 309-15, 2011.

Rodriguez, P., Da Silva, S., Oxburgh, L., Wang, F., Hogan, B.L.M., and Que, J.: BMP signaling in the development of the mouse esophagus and forestomach.
Development. 137 (24): 4171-6, 2010.

Sureban SM, Murmu N, Rodriguez P, May R, Maheshwari R, Dieckgraefe BK, Houchen CW, Anant S:
Functional antagonism between RNA binding proteins HuR and CUGBP2 determines the fate of COX-2 mRNA translation.
Gastroenterology 132 (3): 1055-65, 2007.