Seminar – Daniel J. Salamango, Ph.D.

Our lab is broadly interested in host-pathogen interactions between cellular proteins and viral pathogens. We utilize traditional and “new age” molecular virology approaches (i.e., deep mutational scanning and whole genome CRISPR/Cas9 screening) to study viral protein localization, function, and interactions with host-cell processes to uncover novel mechanisms that facilitate virus replication. In addition, we are also interested in virus-associated disease pathologies, such as virus-induced neuropathy, and elucidating the underlying molecular mechanisms. Finally, as we uncover and explore cellular pathways manipulated by viral pathogens, we also investigate knowledge-gaps associated with how these pathways function in general biology.