Location: Cell Biology, Genetics & Molecular Medicine Discipline, April Risinger, Ph.D. Lab



Leila Takahashi-Ruiz

Graduate Student

Personal Statement:

Hometown: Sendai, Japan
Hobbies: Hobbies include cooking, collecting houseplants, and creating music





B.S. in Biological Sciences
Colorado State University
Fort Collins, CO


Cancer; Pharmacology; Triple Negative Breast Cancer; Immunology; Microtubule-Targeting Agents

Awards & Accomplishments

Postbaccalaureate Research Education Scholar 2018-2019, Virginia Commonwealth University

IMSD Award Recipient 2019-2020, UT Health San Antonio


Fermaintt, C.S, Takahashi-Ruiz, L., Liang, H., Mooberry, S.L., Risinger, A.L. Eribulin activates the cGAS-STING pathway via the cytoplasmic accumulation of mtDNA. Mol Pharmacol. 2021 Jul 26:MOLPHARM-AR-2021-000297. doi: 10.1124/molpharm.121.000297. Epub ahead of print. PMID: 34312217.

Fermaintt, C.S., Peramuna, T., Cai, S., Takahashi-Ruiz, L., Essif, J.N., Grant, C.V., O’Keefe, B.R., Mooberry, S.L., Cichewicz, R.H., Risinger, A.L. Yuanhuacine Is a Potent and Selective Inhibitor of the Basal-Like 2 Subtype of Triple Negative Breast Cancer with Immunogenic Potential. Cancers (2021), 13, 2834.

Lownik, J.C., Wimberly, J.L., Takahashi-Ruiz, L., Martin, R.K. B cell ADAM17 controls T cell independent humoral immune responses through regulation of TACI and CD138. Biochemical and Biophysical Research Communications (2020). 522(2):442-447. DOI: 10.1016/j.bbrc.2019.11.124.