IBMS Physiology and Pharmacology Discipline
Yuguang ‘Roger’ Shi, Ph.D.
Hobbies and Interests:
Tennis, volleyball, swimming, traveling and fluent in spoken Japanese
Utah Valley University - Orem, Utah
John-Paul is working on translational research of aging and aging-related metabolic diseases. His research projects focus on molecular mechanisms underlying the role mitochondrial dysfunction in cellular senescence, aging, and aging-relate diseases using molecular, cellular, metabolic, and transgenic approaches. The overarching goals of his research work is to identify novel treatment and prevention of aging and the related metabolic dysfunctions, including type 2 diabetes and cardiovascular diseases.
Awards & Accomplishments
• Lectures, Posters and Presentations •
American Chemical Society Rocky Mountain Regional Meeting – Westminster, CO. – Oct 2012
Andersen, JP., Wogenstahl, E. and Bernart, M. : Isolation and Structure Elucidation of a Styrylpyrone from the Polypore Mushroom Phaeolus schweinitzii (Poster)
Aster-B coordinates with Arf1 to regulate mitochondrial cholesterol transport https://pubmed.ncbi.nlm.nih.gov/32738348/
Aster-C coordinates with COP I vesicles to regulate lysosomal trafficking and activation of mTORC1 https://pubmed.ncbi.nlm.nih.gov/32648345/
Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson’s diseases https://pubmed.ncbi.nlm.nih.gov/30838774/