Cellular and Integrative Physiology

Ngoni Madungwe

Graduate Student

Personal Statement:

I am a motivated and driven graduate student working in the field of cardiovascular research with the goal of discovering new approaches to treating myocardial infarction. My background is in engineering and I apply my technical background to applications of treating human disease and improving patient outcomes.

Biomedical Engineering Discipline

Lab Association:
Jean C. Bopassa, Ph.D. 



B.S. in Chemical Engineering (Cum Laude), Tufts University, 2013


My research is mainly focused on the role of biomolecules in the function of induced pluripotent stem cell-derived cardiomyocytes. These cells are an exciting option for not only treating cardiovascular diseases, especially myocardial   infarction (heart attack), but also hold promise for disease modeling applications and drug testing. Other projects I work on are aimed at understanding the proteins and mechanisms that impact cardiac mitochondrial function, particularly in instances of ischemia/reperfusion injury.

Awards & Accomplishments

2017    Physiology Dept. Graduate Student Travel Award to AHA 2017 Scientific Sessions, Anaheim, CA;  Dept. of Cell & Int. Physiology, UTHSCSA

2017    BMES-NSBE Student Travel Award to Biomedical Engineering Society 2017 Annual Meeting, Phoenix AZ; National Society of Black Engineers

2017    Cardiovascular Outreach Award; Council on Basic Cardiovascular Sciences 2017 Scientific Sessions, Portland OR; American Heart Association

2017    Honorable mention for poster presentation, Annual Graduate Student Symposium, Physiology Department, UTHSCSA

2017    Featured speaker, UT Health Voices and Speed Networking Night 2017, UTHSCSA

2016    Grand Prize Winner, 3 Minute Thesis Competition; Annual Terry M. Mikiten Graduate Research Symposium, UTHSCSA

2016    Best poster presentation, Annual Graduate Student Symposium, Physiology Department, UTHSCSA


  • American Heart Association
  • Biomedical Engineering Society
  • National Society of Black Engineers


Feng, Y., Madungwe, N.B., da Cruz Junho, C. V. and Bopassa, J.C. (2017) Activation of G protein-coupled estrogen receptor 1 at the onset of reperfusion protects the myocardium against ischemia/reperfusion injury by reducing mitochondrial dysfunction and mitophagy. British Journal of Pharmacology, 174(23):4329-4344. PMCID: PMC5715577.

Boiko, N., Medrano, G., Montano, E., Jiang, N., Madungwe, N.B., Bopassa, J.C., Parrish, J., Hargreaves, K.M., Stockand, J.D. and Eaton, B.A. (2017). Ionic Basis of neuron hyperexcitability in response to vinca alkaloids. PLoS One, 12(10):e0186888. doi: 10.1371/journal.pone.0186888. PMCID: PMC5662086.

Madungwe, N.B., Zilberstein, N.F., Feng, Y. and Bopassa, J.C. (2016). Critical role of mitochondrial ROS is dependent on their site of production on the electron transport chain in ischemic heart. American Journal of Cardiovascular Disease, 6(3), 93-108. PMCID: PMC5030389.