Contact

Location: VA C516.1

Department

Medicine

Antonio R. Anzueto, MD

Professor

Personal Statement:

Birthplace: Guatemala City, Guatemala


Education

Research

AECB
Acute Exacerbations of Chronic Bronchitis


ARDS
Acute Respiratory Distress Syndrome


CAP
Community Acquired Pneumonia


COPD
Chronic Obstructive Pulmonary Disease


Mech Vent
Mechanical Ventilation


Septic shock
Diagnoses and treatment of Septic Shock


VAP
Ventilator Associated Pneumonia


Publications

Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung. Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto AR, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, Victorina Lopez Varela M, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Stockley R, Vestbo J, Wedzicha JA, Agusti A.2017 Mar


Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung. Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto AR, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, Victorina Lopez Varela M, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Stockley R, Vestbo J, Wedzicha JA, Agusti A.2017 Mar


Early efficacy of budesonide/formoterol in patients with moderate-to-very-severe COPD. Calverley PM, Ericksson G, Jenkins CR, Anzueto AR, Make BJ, Persson A, Fageras M.2016 Dec


Early efficacy of budesonide/formoterol in patients with moderate-to-very-severe COPD. Calverley PM, Ericksson G, Jenkins CR, Anzueto AR, Make BJ, Persson A, Fageras M.2016 Dec


Safety and Tolerability of Single Dose Inhaled Dry Powder Tacrolimus in Healthy Subjects. Levine SM, Singh H, Williams R, O`Donnell K., Lang B, Wang Y, Anzueto AR, Talbert R., Peters JI.2013 Oct


Safety and Tolerability of Single Dose Inhaled Dry Powder Tacrolimus in Healthy Subjects. Levine SM, Singh H, Williams R, O`Donnell K., Lang B, Wang Y, Anzueto AR, Talbert R., Peters JI.2013 Oct


Outcome of single lung transplants from the same donor: Pulmonary Twinning. Susanto IS, Sako EY, Anzueto AR, Levine SM, Peters JI, Cronin T, Jenkinson SG, Bryan C.1995 Oct


Outcome of single lung transplants from the same donor: “Pulmonary Twinning”. Susanto IS, Sako EY, Anzueto AR, Levine SM, Peters JI, Cronin T, Jenkinson SG, Bryan C.1995 Oct


Risk Factors for Noninvasive Ventilation Failure in Critically Ill Subjects With Confirmed Influenza Infection. Rodriguez A, Ferri C, Martin – Loeches I, Diaz E, Masclans JR, Gordo F, Sole_violan J, Bodi M, Aviles-Jurado FX, Trefler S, Magret M, Moreno G, Reyes LF, Marin-Corral J, Yevene JC, Esteban A, Anzueto AR, Restrepo MI.2017 Oct


Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling. Reyes LF, Restrepo MI, Hinojosa CA, Soni NJ, Anzueto AR, Babu BL, Gonzalez-Juarbe N, Rodriguez AH, Jimenez A, Chalmers JD, Aliberti S, Sibila O, Winter VT, Coalson JJ, Giavedoni LD, Dela Cruz CS, Waterer GW, Witzenrath M, Suttorp N,, Dube PH,, Orihuela CJ.2017 Sep


ersistent and Newly Developed Chronic Bronchitis Are Associated with Worse Outcomes in Chronic Obstructive Pulmonary Disease. Kim V, Zhao H, Boriek AM, Anzueto AR, Soler X, Bhatt SP, Rennard SI, Wise R, Comellas A, Ramsdell JW, Kinney GL, Han MK, Martinez CH, Yen A, Black-Shinn J, Porszasz J, Criner GJ, Hanania NA, Sharafkhaneh A, Crapo JD, Make BJ,, Silverman EK, Curtis JL.2017 Jul


Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects. Busch R, Hobbs BD, Zhou J, Castaldi PJ, McGeachie MJ, Hardin ME, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Agusti A, Make BJ, Crapo JD, Calverley PM, Donner CF, Lomas DA, Wouters EF, Vestbo J, Tal-Singer R, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Pare PD, Levy RD, Rennard SI, Beaty TH, Hokanson J, Silverman EK, Cho MH, National Emphysema Treatment Trial Genetics, Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-Points, International COPD Genetics Network, COPDGene Investigators.2017 Jul


Chronic Respiratory Infection in Patients with Chronic Obstructive Pulmonary Disease: What Is the Role of Antibiotics?. Miravitlles M, Anzueto AR.2017 Jul


High endocan levels are associated with the need for mechanical ventilation among patients with severe sepsis. Mangat M, Amalakuhan B, Habib S, Reyes LF, Hinojosa CA, Rodriguez AH, Soni NJ, Anzueto A, Levine SM, Peters JI, Aliberti S, Sibila O, Rello J, Witzenrath M, Waterer GW, Martin-Loeches I, Blanquer J, Sanz F, Marcos PJ, Sole-Violan J, Chalmers JD, Feldman C, Wunderink RG, Cruz CSD, Orihuela CJ,, Restrepo MI.2017 Jul


Blood eosinophil count and exacerbation risk in patients with COPD. Kerkhof M, Sonnappa S, Postma DS, Brusselle G, Agusti A,, Anzueto A, Jones R, Papi A, Pavord I, Pizzichini E, Popov T, Roche N, Ryan D, Thomas M, Vogelmeier C, Chisholm A, Freeman D, Bafadhel M, Hillyer EV, Price DB.2017 Jul


Optimizing bronchodilation in the prevention of COPD exacerbations. Miravitlles M, Anzueto AR, Jardim JR.2017 Jun


The effect of COPD severity and study duration on exacerbation outcome in randomized controlled trials. Eriksson G, Calverley PM, Jenkins CR, Anzueto AR, Make BJ, Lindberg M, Fager?s M, Postma DS.2017 May


The effect of indacaterol/glycopyrronium versus tiotropium or salmeterol/fluticasone on the prevention of clinically important deterioration in COPD. Anzueto AR, Vogelmeier CF, Kostikas K, Mezzi K, Fucile S, Bader G, Shen S, Banerji D, Fogel R.2017 May


Effectiveness and safety of mycophenolate mofetil in idiopathic pulmonary fibrosis. Nambiar AM, Anzueto AR, Peters JI.2017 Apr


Association between ventilatory settings and development of acute respiratory distress syndrome in mechanically ventilated patients due to brain injury. Tejerina E, Pelosi P, Muriel A, Pe?uelas O, Sutherasan Y, Frutos-Vivar F, Nin N, Davies AR, Rios F, Violi DA, Raymondos K, Hurtado J, Gonzalez M, Du B, Amin P, Maggiore SM,, Thille AW, Soares MA, Jibaja M, Villagomez AJ, Kuiper MA, Koh Y, Moreno RP, Zeggwagh AA, Matamis D, Anzueto AR, Ferguson ND, Esteban A.2017 Apr


Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary. Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto AR, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, Lopez Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agusti A.2017 Apr


Pathophysiology of dyspnea in COPD. Anzueto AR, Miravitlles M.2017 Apr


LABA/LAMA combinations versus LAMA monotherapy or LABA/ICS in COPD: a systematic review and meta-analysis. Rodrigo GJ, Price D, Anzueto AR, Singh D, Altman P, Bader G, Patalano F, Fogel R, Kostikas K.2017 Mar


Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary. Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto AR, Barnes PJ, Bourbeau J, Celli BR, Chen R,, Decramer M, Fabbri LM, Frith P, Halpin DM, Lopez Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agusti A.2017 Mar


Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline. Wedzicha JA Ers Co-Chair, Miravitlles M,, Hurst JR, Calverley PM, Albert RK, Anzueto AR, Criner GJ,, Papi A, Rabe KF, Rigau D, Sliwinski P, Tonia T, Vestbo J, Wilson KC,, Krishnan JA Ats Co-Chair.2017 Mar


Acute Exacerbations and Lung Function Loss in Smokers with and without Chronic Obstructive Pulmonary Disease. Dransfield MT, Kunisaki KM, Strand MJ, Anzueto AR, Bhatt SP, Bowler RP, Criner GJ, Curtis JL, Hanania NA, Nath H, Putcha N, Roark SE, Wan ES, Washko GR, Wells JM, Wendt CH, Make BJ.2017 Feb


A new two-step algorithm for the treatment of COPD. Miravitlles M, Anzueto AR.2017 Feb


Severe hypercapnia and outcome of mechanically ventilated patients with moderate or severe acute respiratory distress syndrome. Nin N, Muriel A, Penuelas O, Brochard L, Lorente JA, Ferguson ND, Raymondos K, Rios F, Violi DA, Thrille AW, Gonzalez M, Villagomez AJ, Hurtado J, Davies AR, Du B, Maggiore SM, Soto L, D`Empaire G, Matamis D, Abroug F, Moreno RP, Soares MA, Arabi Y, Sandi F, Jibaja M, Amin P, Koh Y, Kuiper MA, Bulow HH, Zeggwagh AA, Anzueto AR, Sznajder F, Esteban A.2017 Feb


Assessing Short-term Deterioration in Maintenance-naive Patients with COPD Receiving Umeclidinium/Vilanterol and Tiotropium: A Pooled Analysis of Three Randomized Trials. Maleki-Yazdi MR, Singh D, Anzueto AR, Tombs L, Fahy WA, Naya I.2017 Jan


Endothelial Adhesion Molecules and Multiple Organ Failure in Patients With Severe Sepsis. Amalakuhan B, Habib SA, Mangat M, Reyes LF, Rodriguez AH, Hinojosa CA, Soni NJ, Gilley RP, Bustamante CA, Anzueto AR, Levine SM, Peters JI, Aliberti S, Sibila O, Chalmers JD, Torres A, Waterer GW, Martin-Loeches, Bordon J, Blanquer J, Sanz F, Marcos PJ, Rello J, Ramirez J, Sole-Violan, Luna CM, Feldman C, Witzenrath M, Wunderink RG, Stolz D, Wiemken TL, Shindo Y, Dela Cruz CS, Orihuela CJ, Restrepo MI.2016 Dec


Complication of Community-Acquired Pneumonia (Including Cardiac Complications). Restrepo MI, Reyes LF, Anzueto AR.2016 Dec


Early efficacy of budesonide/formoterol in patients with moderate-to-very-severe COPD. Calverley PM, Eriksson G, Jenkins CR, Anzueto AR, Make BJ, Persson A, Fager?s M, Postma DS.2016 Dec


Health Care-associated pneumonia in the intensive care unit:Guideline-concordant antibiotics and outcomes. Attridge RT, Frei CR, Pugh MJ, Lawson KA, Ryan L, Anzueto AR, Metersky ML, Restrepo MI, Mortensen EM.2016 Dec


Health care-associated pneumonia in the intensive care unit: Guideline-concordant antibiotics and outcomes. Attridge RT, Frei CR, Pugh MJ, Lawson KA, Ryan L, Anzueto AR, Metersky ML, Restrepo MI, Mortensen EM.2016 Dec


A Non-Human Primate Model of Severe Pneumococcal Pneumonia. Reyes LF, Restrepo MI, Hinojosa CA, Soni NJ, Shenoy AT, Gilley RP, Gonzalez-Juarbe N, Noda JR, Winter VT, de la Garza MA, Shade RE, Coalson JJ, Giavedoni LD, Anzueto AR, Orihuela CJ.2016 Nov


A Non-Human Primate Model of Severe Pneumococcal Pneumonia. Reyes LF, Restrepo MI, Hinojosa CA, Soni NJ, Shenoy AT, Gilley RP, Gonzalez-Juarbe N, Noda JR, Winter VT, de la Garza MA, Shade RE, Coalson JJ, Giavedoni LD, Anzueto A, Orihuela CJ.2016 Nov


TIOtropium Safety and Performance In Respimat? (TIOSPIRTM ): Analysis of Asian cohort of COPD patients. Zhong N, Moon HS, Lee KH, Mahayiddin AA, Boonsawat W, Isidro MG, Bai C, Mueller A, Metzdorf N, Anzueto AR.2016 Nov


Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting β2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE(2)SPOND). Martinez FJ, Rabe KF, Sethi S, Pizzichini E, McIvor A, Anzueto AR, Alagappan VK, Siddiqui S, Rekeda L, Miller CJ, Zetterstrand S, Reisner C, Rennard SI.2016 Sep


Blood eosinophil count and pneumonia risk in patients with chronic obstructive pulmonary disease: a patient-level meta-analysis. Pavord ID, Lettis S, Anzueto AR, Barnes N.2016 Sep


Effects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting β2-agonist fixed-dose combination: RE(2)SPOND rationale and study design. Rennard SI, Martinez FJ, Rabe KF, Sethi S, Pizzichini E, McIvor A, Siddiqui S, Anzueto AR, Zhu H.2016 Aug


Tiotropium safety in `real-world` populations: Response to Schmiedl, et al. in the British Journal of Clinical Pharmacology. Wise R, Anzueto AR, Dahl R, Dusser D, Calverley P.2016 Aug


Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease. Bhatt SP, Soler X, Wang X, Murray S, Anzueto AR, Beaty TH, Boriek AM, Casaburi R, Criner GJ, Diaz AA, Dransfield MT, Curran-Everett D, Galban CJ, Hoffman EA, Hogg JC, Kazerooni EA, Kim V, Kinney GL, Lagstein A, Lynch DA, Make BJ, Martinez FJ, Ramsdell JW, Reddy R, Ross BD, Rossiter HB, Steiner RM, Strand MJ, Van Beek EJ, Wan ES, Washko GR, Wells JM, Wendt CH, Wise RA, Silverman EK, Crapo JD, Bowler RP, Han MK.2016 Jul


Effect of tiotropium on COPD exacerbations: A systematic review. Halpin DM, Vogelmeier C, Pieper MP, Metzdorf N, Richard F, Anzueto AR.2016 May


Prediction and Outcome of Intensive Care Unit-Acquired Paresis. Pe?uelas O, Muriel A, Frutos-Vivar F, Fan E, Raymondos K, Rios F, Nin N, Thille AW, Gonzalez M, Villagomez AJ, Davies AR, Du B, Maggiore SM, Matamis D, Abroug F, Moreno RP, Kuiper MA, Anzueto AR, Ferguson ND, Esteban A.2016 Apr


Early response to inhaled bronchodilators and corticosteroids as a predictor of 12-month treatment responder status and COPD exacerbations. Calverley PM, Postma DS, Anzueto AR, Make BJ, Eriksson G, Peterson S, Jenkins CR.2016 Feb


Differences in outcomes between GOLD groups in patients with COPD in the TIOSPIR(?) trial. Dusser D, Wise RA, Dahl R, Anzueto AR, Carter K, Fowler A, Calverley PM.2016 Jan


Association of azithromycin with mortality and cardiovascular events among older patients hospitalized with pneumonia. Mortensen EM, Halm EA, Pugh MJ, Copeland LA, Metersky M, Fine MJ, Johnson CS, Alvarez CA, Frei CR, Good C, Restrepo MI, Downs JR, Anzueto AR.2014 Jun


The need to further understand who gets hospitalized for a COPD exacerbation. Maselli DJ, Anzueto A.2012 Jun


Clinical evaluation of the role of ceftaroline in the management of community acquired bacterial pneumonia. Maselli DJ, Fernandez J, Whong CY, Echevarria K, Nambiar AM, Anzueto AR, Restrepo MI.2012 Feb


Evaluation of withdrawal of maintenance tiotropium in COPD. Adams SG, Anzueto A, Briggs DD, Leimer I, Kesten S.2009 Oct


A pharmacotherapeutic approach to improving health-related quality of life for patients with chronic obstructive pulmonary disease. Adams SG, Anzueto AR.2009 May


Systematic review of the Chronic Care Model in chronic obstructive pulmonary disease prevention and management. Adams SG, Smith PK, Allan PF, Anzueto AR, Pugh JA, Cornell JE.2007 Mar


Antibiotic therapy in acute exacerbation of chronic bronchitis: The antibiotics. Part 2. Adams SG, Anzueto AR.2002 Jan


Antibiotic therapy in acute exacerbations of chronic bronchitis. Adams SG, Anzueto A, Anzueto AR.2000 Sep


Acute Kidney Injury in Mechanically Ventilated Patients: The Risk Factor Profile Depends on the Timing of Aki Onset. Lombardi R, Nin N, Nin N, Pe?uelas O, Ferreiro A, Rios F, Marin MC, Raymondos K, Lorente JA, Koh Y,, Hurtado J, Gonzalez M, Abroug F, Jibaja M, Arabi Y, Arabi Y, Matamis D, Anzueto AR, Esteban A.2017 Apr


Complication of Community-Acquired pneumonia(including cardiac complications). Anzueto AR.2016 Dec


Assessing short-term deterioration in Maintenance-naive patients with COPD reveiving umeclidinium. Anzueto AR.2016 Dec


Association between ventilatory settings and development of acute respiratory distress syndrome in mechanicaly ventilated patients due to brain injury. Anzueto AR.2016 Nov


Appointments

9/2004: Professor – University of Texas Health Science Center at San Antonio, San Antonio


1/2000: Chief, Pulmonary Section – The South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division, San Antonio


9/1996: Medical Director, Pulmonary Function Laboratory – The South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division, San Antonio


1/1995: Director, Pulmonary Function Laboratory – The South Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division, San Antonio


1/1995: Director Pulmonary Function Lab – University Hospital, San Antonio


1/1995: Medical Director, Respiratory Therapy Department – The South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division, San Antonio


1/1995: Medical Director Bronchoscopy Laboratory – The South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division, San Antonio


7/1992: Director Pulmonary Service Spinal Cord Unit – The South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division, San Antonio


7/1992: Staff Physician – The South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division, San Antonio


7/1992: Staff Physician – University Hospital, San Antonio


10/1983: Adjunct Scientist – Southwest Foundation for Biomedical Research, San Antonio