Timothy Tseng, M.D.
Medical Director at Robert B. Green (RBG)
Dr. Timothy Tseng graduated Magna Cum Laude with Highest Honors from Harvard University with an AB degree in Biochemical Sciences. He attended Duke University School of Medicine for both medical school and urology residency. Following residency, Dr. Tseng completed a fellowship in Endourology and Laparoscopy at the University of California San Francisco where he received specialized training in the surgical and medical management of kidney stones and minimally invasive urology. Dr. Tseng joined the Department of Urology in 2010.
M.D., Duke University School of Medicine (2003)
AB, Harvard University (1999)
University of California San Francisco, Fellowship, Endourology, and Laparoscopy (2010)
Duke University School of Medicine, Residency, Urology (2009)
Duke University School of Medicine, Internship, General Surgery (2004)
Dr. Tseng has extensive experience in the endoscopic and percutaneous treatment of urinary stones, cancers of the urinary tract, and urinary obstruction. He is one of the few urologists in the country who performs his own percutaneous access to the kidney for removal of large kidney stones. As part of the Comprehensive Kidney Stone Center, Dr. Tseng also performs complete metabolic stone evaluations to guide focused dietary and medical interventions to help prevent future kidney stones. In addition to his work with kidney stones, Dr. Tseng also has extensive experience with other minimally invasive urological procedures including laparoscopic pyeloplasty and nephrectomy.
Dr. Tseng is interested in the etiology of stone disease, and also at looking at ways to improve patient care with stones. Dr. Tseng has been involved in several studies focused on clinical factors that result in a predisposition to kidney stones. To better understand the different potential causes of urolithiasis, Dr. Tseng examined the laterality of nephrocalcinosis and found that it was significantly associated with the dependent side that a patient sleeps upon primarily. Combined with a study that demonstrates the significantly increased perfusion to the dependent kidney, the differences in localization are felt to potentially be due to increased vascular injury to the dependent kidney, a theory distinct from the mineral supersaturation hypothesis of the origin of urinary stones. He also studied the association between dietary habits and kidney stone incidence and demonstrated that a higher intake of calcium and lower intake of sodium were associated with lower kidney stone incidence. Although counter-intuitive, the protective nature of calcium intake supports the theory that calcium can bind dietary oxalate to form insoluble compounds that cannot be absorbed from the gastrointestinal tract. At present, he has a clinical trial ongoing to investigate the utility of serum MicroRNA-21 (miR-21) levels as a novel biomarker for the severity of ureteral obstruction in the setting of an acute ureteral calculus. This is a first step toward the development of a more objective method of gauging the severity of ureteral obstruction and has the potential to change the way urologists manage acute ureteral calculi.