Principal Investigator:
Okeanis Vaou, MD

https://clinicaltrials.gov/study/NCT04994015

Type of Study:
Registry/ Observational

Summary
This study aims to retrospectively compare cases of SUDEP with matched control subjects cared for by the same epilepsy center to identify risk factors and potential biomarkers associated with SUDEP.

Link to Sponsor’s Website:
https://www.parkinson.org/advancing-research/our-research/pdgeneration

Study Coordinator:
Omalys Biggs
Office: 210-450-8456
Email: biggsrodrigu@uthscsa.edu

Principal Investigator:
Anjali Sivaramakrishnan

https://clinicaltrials.gov/study/NCT06133283

Type of Study:
Interventional

Summary
This study aims to determine the effects of aerobic exercise as a primer to add-on virtual reality (VR)-based rehabilitation on balance, postural control and neuroplasticity (ability of brain to adapt in structure and function) in individuals with Parkinson’s disease (PD). This study will utilize two groups – one group will receive the exercise and VR, while the other group will receive stretching exercise and VR over eight weeks. The study team will administer outcomes at baseline, post-intervention (8 weeks) and follow-up (6 weeks after post-assessment)

Study Coordinator:
Carolyn Paiz
Office: 210-450-8830
Email: paizc@uthscsa.edu

 Principal Investigator:
Okeanis Vaou, MD

https://clinicaltrials.gov/study/NCT02071134

Type of Study:
Registry/ Observational

Summary
The purpose of this registry is to compile characteristics of world-wide outcomes for the use of Boston Scientific’s commercially available Vercise DBS system in the treatment of Parkinson’s disease.  Subjects’ improvement in disease symptoms and overall Quality of life will be assessed during the study following DBS and compared with baseline. Additionally, the utilization of Image Guided Programming (IGP) when used as a planning tool for programming of patients is also evaluated

Link to Sponsor’s Website:
https://www.bostonscientific.com/en-US/search.html#q=vercise%20trial&first=10

Study Coordinator:
Carolyn Paiz
Office: 210-450-8830
Email: paizc@uthscsa.edu

 Principal Investigator:
Okeanis Vaou, MD

https://clinicaltrials.gov/study/NCT06107426

Type of Study:
Observational

Summary
Parkinson’s disease (PD) is a neurological condition, which affects the brain.
PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some symptoms of PD are tremors, stiffness, and slowness of movement. The purpose of this study is to evaluate how effective ABBV-951 is in treating adult participants with advanced PD in real world setting.

Study Coordinator:
Carolyn Paiz
Office: 210-450-8830
Email: paizc@uthscsa.edu

 Principal Investigator:
Okeanis Vaou, MD

https://clinicaltrials.gov/study/NCT04284436

Type of Study:
Interventional/Randomized Control

Summary
This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax or 2)80-85% HRmax 4 times per week. The primary objective is to test whether the progression of the signs of Parkinson’s disease is attenuated at 12 months in among persons who have not initiated medication for Parkinson Disease (PD) when they perform high-intensity endurance treadmill exercise.

Link to Sponsor’s Website:
https://www.sparx3pd.com/home/volunteer

Study Coordinator:
Carolyn Paiz
Office: 210-450-8830
Email: paizc@uthscsa.edu