Thomas Patterson posing for his profile photo.

T. Tyler Patterson, MD



Undergraduate (BA in Economics) – Trinity University, 2011-2015

Medical School

Medical School (MD) – University of Texas Health Science Center San Antonio, 2015-2019

Graduate School

Residency – University of Texas Health Science Center San Antonio, 2019-present)

Professional Interests

Traumatic Brain Injury and Gut Microbiome
I have multiple projects from this topic focusing around the interaction between the gut microbiome and traumatic brain injury. The focus has been on immunological responses to CNS trauma that results in gut alterations, which in turn have inflammatory consequences on the CNS.

Cranioplasty after Decompressive Hemicraniectomy
A retrospective study at this time on the rate of cranioplasty infection or resorption rates based on mechanism of injury, interval time, size of craniectomy, etc. We have statistical significance at this time, and are planning to expand our project scale.

Wallace DJ, Sayre NL, Patterson TT, Nicholson SE, Hilton D, Grandhi R. Spinal cord injury and the human microbiome: beyond the brain-gut axis. Neurosurg Focus. 46(3). 2019.
Johnson WC, Ishaque M, Patterson TT, Grandhi R. A Radiographic Evaluation of Bone Flap Size Following Autologous Craniplasty. AANS E-Posters 2019.

Patterson TT, Nicholson-Roberts S, Wallace D, Hawryluk G, Grandhi R. Complex feed-forward and feed-back mechanisms underlie the relationship between traumatic brain injury and the gut–microbiota–brain axis. Shock. doi: 10.1097/SHK.0000000000001278. 2018.

Zhu C, Grandhi R, Patterson TT, Nicholson SE. A Review of Traumatic Brain Injury and the Gut Microbiome: Insights into Novel Mechanisms of Secondary Brain Injury and Promising Targets for Neuroprotection. Brain Sci. 8(6). 2018.

Kemal CJ, Patterson TT, and Molina DK. Deaths due to sharp force injuries in Bexar County, Texas, with respect to manner of death. Am J Forensic Med Pathol. 34(3): 253-9. 2013.

Professional Affiliations

Alpha Omega Alpha Medical Honor Society

American Association of Neurological Surgeons (AANS)

Congress of Neurological Surgeons (CNS)

Texas Medical Association (TMA)

Awards & Accomplishments

2018-2019: Alpha Omega Alpha Medical Honor Society, Member

2018-2019: Neurosurgery Senior Student Achievement Award, UTHSCSA

2015-2017 : McNutt Gross Anatomy Award, Honorable Mention, UTSHCSA

2015: Summa Cum Laude, Graduation Honors, Trinity University

2011-2015: Dean’s List, Trinity University