Alison Clark

Postdoctoral Fellow

Ph.D., Cellular and Structural Biology (Cancer Biology)
UT Health San Antonio
San Antonio, Texas
Lab: 210-567-6674
Email: clarka4@uthscsa.edu
Lab Association: Susan Mooberry, Ph.D.
Research Interests

• breast cancer                               • signal transduction
• transcription regulation

Research Summary
Information Pending
 
Accomplishments, Awards and Honors

  • Institutional Research and Academic Career Development Award (IRACDA) Scholar (K12GM11726), UT Health Science Center – San Antonio, TX – 2016 to Present
  • 1st Place Research Award to Postdoctoral Fellow, Department of Molecular Medicine, UT Health Science Center – San Antonio, TX – 2016
  • Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Training Grant (T32DE014318), UT Health Science Center – San Antonio, TX – 2013 to 2016
  • Travel Award to attend American Society for Cell Biology Annual Meeting, Graduate School of Biomedical Sciences, UT Health Science Center – San Antonio, TX – 2015
  • 2nd Place Research Award Graduate Student, Department of Molecular Medicine, UT Health Science Center – San Antonio, TX – 2015
  • 2nd Place Research Award Graduate Student, Department of Cellular and Structural Biology, UT Health Science Center – San Antonio, TX – 2015
  • Greg Treibs Memorial Scholarship, UT Health Science Center – San Antonio, TX – 2012
  • Dean’s Excellence Award, Graduate School of Biomedical Sciences, UT Health Science Center – San Antonio, TX – 2011

 
Appointments, Boards, Committees and Memberships

  • 2016–Present – American Association for the Advancement of Science
  • 2015–Present – American Association for Cancer Research
  • 2014–2016 – American Society for Biochemistry and Molecular Biology
  • 2014–2016 – American Society for Cell Biology
  • 2013–2016 – American Association for Dental Research
  • 2012–2016 – Society for Advancement of Chicanos and Native Americans in Science

Selected Publications

  • Clark AD, Oldenbroek M, Wang Y, Spaeth JM, Jin VX and Boyer TG (2016) Mediator kinase module transduces oncogenic Wnt/-catenin signaling through control of super enhancer activity. Manuscript in preparation.
  • Clark AD, Oldenbroek M and Boyer TG. (2015) Mediator kinase module and human tumorigenesis Crit Rev Biochem Mol Biol. 50(5): 393-426
  • Kämpjärvi K, Kim NH, Keskitalo S, Clark AD, von Nandelstadh P, Turunen M, Heikkinen T, Park MJ, Mäkinen N, Kivinummi K, Lintula S, Hotakainen K, Nevanlinna H, Hokland P, Böhling T, Bützow R, Böhm J, Mecklin, JP, Järvinen H, Porkka K, Visakorpi T, Taipale J, Varjosalo M, Boyer TG and Vahteristo P. (2015) Somatic MED12 mutations in prostate cancer and uterine leiomyomas promote tumorigenesis through distinct mechanisms Prostate Jan;76(1):22-31
  • Kämpjärvi K, Park MJ, Mehine M, Kim NH, Clark AD, Bützow R, Böhling T, Böhm J, Mecklin JP, Järvinen H, Tomlinson IPM, van der Spuy ZM, Sjöberg J, Aaltonen LA, Boyer TG, and Vahteristo P. (2014) MED12 exon 1 mutations in uterine leiomyomas Hum Mutat Sep;35(9):1136-41
  • Turunen M, Spaeth JM, Keskitalo S, Park MJ, Kivioja T, Clark AD, Mäkinen N, Vähärautio A, Aavikko M, Kämpjärvi K, Nurkkala H, Vahteristo P, Kim CA, Aaltonen LA, Varjosalo M, Taipale J and Boyer TG. (2014) Uterine leiomyoma-linked MED12 mutations disrupt Mediator-associated CDK activity Cell Rep., May 8;7(3):654–660. PMCID: PMC4041330
  • Selected Abstracts
  • Clark AD, Mooberry SL : Effects of microtubule targeting agents on E­cadherin signaling pathways in breast cancer cells Department of Pharmacology Graduate Student Symposium, UTHSCSA, San Antonio, TX – October 2016 (Poster Presentation)
  • Clark AD, Oldenbroek M, Wang Y, Spaeth JM, Jin VX, Boyer TG : Mediator as a transducer of oncogenic Wnt/-catenin signaling American Association for Cancer Research, New Orleans, LA. – April 2016 (Poster Presentation; T32 Travel Allowance)
  • Clark AD, Oldenbroek M, Wang Y, Spaeth JM, Gao F, Jin VX, Boyer TG : Mediator kinase modulates oncogenic WNT/β-Catenin signaling through regulation of super-enhancer function Molecular Medicine Annual Research Day, UTHSCSA, San Antonio, TX – Oct 2016 (Poster Presentation; 1st Place Research Award)
  • Clark AD, Oldenbroek M, Wang Y, Spaeth JM, Jin VX, Boyer TG : Mediator kinase module transduces oncogenic Wnt/-catenin signaling through control of super enhancer activity Annual Dental Science Symposium, UTHSCSA, San Antonio, TX – Feb 2016 (Poster Presentation)
  • Clark AD, Oldenbroek M, Spaeth JM, Gao F, Boyer TG : Mediator as a transducer of oncogenic Wnt/- catenin signaling American Society for Cell Biology, San Diego, CA – 2015 (Oral Presentation; GSBS Travel Award)