Seminar – Susan K. Wood, Ph.D.
Event Date & TimeOctober 19, 2022 at 12 Noon
DEPARTMENT OF PHARMACOLOGY
Wednesday, October 19, 2022
12:00pm – 444B LSOM
Susan K. Wood, Ph.D.
Department of Pharmacology, Physiology & Neuroscience
School of Medicine Columbia
University of South Carolina
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About the Speaker(s)
Project #1—Cytokines in monoaminergic nuclei regulating susceptibility to social defeat (American Heart Association, Scientist Development Grant) This project seeks to identify regions in the brain that may function differently in susceptible versus resilient individuals to promote cardiovascular disease and psychological disorders in the face of stress. We have identified a critical role for neuroinflammation in susceptibility to social stress and these studies manipulate the activity of inflammatory cytokines in the brain to determine their role in mediating increased risk of stress-related pathology.
Project #2—Identifying the neuroinflammatory pathways driving increased stress susceptibility in females (NARSAD Young Investigator Award; bbrfoundation.org) Females are more susceptible to stress-related disorders compared with men. This project is focused on identifying signaling cascades regulating neuroinflammation within females undergoing social stress as a mechanism to reduce stress-susceptibility.
Project #3—Estrogen-mediated mechanisms of stress susceptibility. The overall goal of this project is to identify how ovarian hormones interact with stress-related neurochemicals within the stress sensitive brain region, the central amygdala, to increase stress susceptibility.