Welcome from our Chairman

Manzoor A. Bhat, M.S., Ph.D
Professor and Chair
Zachry Distinguished Chair in Neurosciences

The Department of Cellular and Integrative Physiology is a basic science department in the Long School of Medicine at the University of Texas Health San Antonio. The Department was founded in 1972 and is renowned for its seminal contributions in many scientific areas including cardiovascular physiology, neurophysiology and the physiological basis of aging. We use state of the art genetic and molecular methodologies in combination with optical tools to understand the mechanisms that underlie neural circuitry, tissue and cellular physiology in normal health; and how they go awry in injuries or diseases. Several cutting-edge research areas being actively pursued include ion channel physiology and modulation, neuromodulatory behavioral mechanisms, glial biology and role of glia in disease, traumatic brain injury, neurovascular mechanisms of cardiac function, cardioprotection pathways, renal salt homeostasis and age-related neurological pathologies.

Our mission is to carry out high impact scholarly investigations that open up new frontiers in our quest to uncover fundamental principles of biological processes. As part of that mission, we provide classroom education and hands on laboratory training to the next generation of physicians and scientists. Our trainees include medical, undergraduate and graduate students and postdoctoral fellows. The graduate students are admitted through a highly competitive admission process under the Integrated Biomedical Sciences Program.

The Department of Cellular and Integrative Physiology recently led the charge to establish the Mouse Genome Engineering and Transgenic Facility, as part of building institutional infrastructure for investigators at the UT Health, San Antonio. This facility now provides genetically modified mouse models as unique tools for investigators to delineate the functions of genes and pathways in a vertebrate system, which is highly relevant to human health and disease.

As Chair of the Department, it is my responsibility to provide support, mentoring and effective leadership in an inclusive and collaborative environment. In recent years, the Department has seen a steady increase in extramural funding and vibrant growth with the recruitment of outstanding junior faculty with expertise in multiple scientific areas. Every member of the Physiology family matters and strives to achieve excellence. Together we will ensure that the Department of Cellular and Integrative Physiology makes a substantial scientific impact at home within the UT System and at the national level.

Thank you for visiting our web site, and I encourage you to contact our faculty for additional information.

In Memory of Edward Joseph Masoro, Ph.D. (1924-2020)

Edward J. Masoro, Professor Emeritus, Department of Physiology, passed away on July 11, 2020 at the age of 95.  He was the founding Chair of the Department of Physiology (renamed Department of Cellular and Integrative Physiology) and founder of the Aging Research and Education Center (AREC) that ultimately became the Sam and Ann Barshop Institute for Longevity and Aging Studies. Ed was a vital part of our research and education programs and his wisdom and love of science will be sorely missed.

Ed remained engaged as a true scientist attending Departmental seminars until a year ago, when his health declined. His contributions to our University have a lasting impact and we hope to continue on his legacy.

A Tribute from a Friend