Postdoctoral Fellow Open Positions

Postdoctoral Position to Investigate Mechanisms of Cardioprotection

Overview/Job Description. A postdoctoral position is immediately available to study the mechanisms underlying mitochondria-induced cardioprotection in the laboratory of Dr. Jean C. Bopassa, Department of Cellular and Integrative Physiology, University of Texas Health Science Center, San Antonio. The Bopassa Lab uses the Langendorff preparation (ex-vivo), LAD occlusion (in vivo) as well as in vitro and organelle (mitochondria, ER) models to investigate the role of mitochondria in cardioprotection. Other techniques used in the lab include measures of the mitochondrial function, molecular biology, biochemistry, immumocytochemistry, confocal and electron microscopy.

Qualifications. Available positions are funded by a National Institutes of Health training program (T32) with training opportunities in the fields of atherosclerosis, cerebrovascular diseases, myocardial infarction and hypertension. Information about the training program and its faculty can be found at www.CVtrainingTexas.org. Highly motivated early-career scientists and physicians with interests in basic cardiovascular biology and mechanisms of disease are encouraged to apply. Experience in rodent’s surgery is highly desirable. Successful applicants will receive training in cutting edge technologies prominent in modern research. At the time of appointment, trainees must hold an advanced academic/professional degree (e.g. DDS, DVM, MD or PhD) and be a U.S. citizen or green card holder. Underrepresented minorities are encouraged to apply.

Salary is commensurate with experience and accomplishments starting at NIH pay scale.

Interested candidates should submit a curriculum vitae, a list of three references and a cover letter stating career goals and research interests to:

Jean C. Bopassa, MS, PhD, FAHA
Department of Physiology, School of Medicine,
University of Texas Health Science Center at San Antonio, 78229.
Email: BOPASSA@uthscsa.edu

All Postdoctoral appointments are designated as security sensitive positions.

The University of Texas Health San Antonio is an Equal Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities.

Postdoctoral Position for Autonomic Neurophysiology In Epilepsy

Overview/Job Description. The Department of Cellular and Integrative Physiology in the Long School of Medicine at the University of Texas Health Science Center San Antonio is seeking highly motivated postdoctoral fellows to engage in ongoing studies to investigate the effects of stress and epilepsy on brainstem autonomic motor output as it relates to sudden death associated with epilepsy in the laboratory of Dr. Carie Boychuk. We have a highly interactive and dynamic research group that evaluates autonomic circuits in an integrative fashion by testing outcomes at the level of individual cell(s), circuit analysis, and whole-animal neurophysiology. We use a variety of techniques including  electrophysiology (both single cell and vagal nerve recordings), fluorescent/laser/light microscopy, radio telemetry, molecular biology, and opto/chemogenetics.

Qualifications. Applicants should have a PhD and/or MD in neuroscience, physiology or related fields. Applicants who anticipate to defend their thesis in the near future are also encouraged to apply. We are seeking individuals with a demonstrated record of careful experimental methods, high-quality publications, excellent written and communication skills and an ability to design and perform research in an independent manner. Several NIH training programs are also available through  the  institution  to  qualified  candidates.  Experience in whole-cell patch clamp electrophysiology and whole animal neurophysiology is preferred but not required. All training can and will be provided. Underrepresented minorities are encouraged to apply.

Salary is commensurate with experience and accomplishments starting at NIH pay scale. Additional  information  regarding  our  laboratory  and  scientific  interests are at https://physiology.uthscsa.edu/team-member/carie-r-boychuk-ph-d/ and our Department within UT Health San Antonio at physiology.uthscsa.edu.

In the email application please include CV with publications, and detailed contact information for 3 references to:

Carie R. Boychuk, Ph.D.
Department of Cellular and Integrative Physiology UT Health San Antonio 78229
Email: BOYCHUKC@uthscsa.edu

All postdoctoral appointments are designated as security sensitive positions.

UT Health San Antonio is an Equal Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities.

Postdoctoral Position for Autonomic Neurophysiology

Overview/Job Description. The Department of Cellular and Integrative Physiology in the Long School of Medicine at the University of Texas Health San Antonio is seeking highly motivated postdoctoral fellows to engage in ongoing studies to investigate the role of vagal motor output in health and disease of cardiovascular function in the laboratory of Dr. Carie Boychuk. We have a highly interactive and dynamic research group that evaluates autonomic circuits in an integrative fashion by testing outcomes at the level of individual cell, cell network, and whole-animal physiology. We use a variety of techniques including electrophysiology (both single cell and vagal nerve recordings), fluorescent/laser/light microscopy, radio telemetry, molecular biology, and opto/chemogenetics.

Qualifications. Applicants should have a PhD and/or MD in neuroscience, physiology or related fields. Applicants who anticipate to defend their thesis in the near future are also encouraged to apply. We are seeking individuals with a demonstrated record of careful experimental methods, high-quality publications, excellent written and communication skills and an ability to design and perform research in an independent manner. Several NIH training programs are also available through the institution to qualified candidates. Experience in whole-cell patch clamp electrophysiology and whole animal neurophysiology is preferred but not required. Underrepresented minorities are encouraged to apply.

Salary is commensurate with experience and accomplishments starting at NIH pay scale. Additional information regarding our laboratory and scientific interests are at https://physiology.uthscsa.edu/team-member/carie-r-boychuk-ph-d/ and our Department within UT Health San Antonio at physiology.uthscsa.edu.

In the email application please include a cover letter that describes research experience and states career goals, CV with publications, and detailed contact information for 3 references to:

Carie R. Boychuk, Ph.D.

Department of Cellular and Integrative Physiology

UT Health San Antonio 78229

Email: BOYCHUKC@uthscsa.edu

All Postdoctoral appointments are designated as security sensitive positions.

The University of Texas Health San Antonio is an Equal Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities.

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Postdoctoral Fellowship Position in Neurobiology of Autism at the University of Texas Health Science Center at San Antonio

This posting is to fill an open postdoctoral fellowship position in the laboratory of Hye Young Lee, PhD in the Department of Cellular & Integrative Physiology, Long School of Medicine. The Lee Lab studies the molecular neurobiology and etiology of Autism Spectrum Disorder (ASD) and related neuropsychiatric disorders, using a range of cutting-edge molecular, cellular and integrative approaches on multiple topics including inflammation, development and gene editing therapeutics. ASD forms a heterogeneous neurodevelopmental syndrome characterized by deficits in language development/social interactions and repetitive behavior/restricted interests. ASD likely arises from a complex combination of genetics and risk factors. However, it is possible that certain aspects of ASD molecular pathophysiology can determine the underlying neurobiological basis of ASD. And, understanding underlying mechanisms will help not only understanding the basis of these disorders, but also will contribute to develop therapeutic treatments for ASD.

The Lee Lab focuses on: 1) identifying the molecular mechanisms responsible for the pathophysiology of ASD and related disorders, and using these mechanisms to rescue behavioral dysfunction in mouse models, 2) elucidating specific autistic behaviors, including social communication deficits and repetitive behaviors, and identifying the brain region(s) and neuron groups underlying these behavioral deficits in mouse models, and 3) developing potential therapeutic treatments for ASD by targeting gene regulation with small molecules and CRISPR using autism patient cells and autism mouse models. To address these questions, our lab employs molecular and cellular neurobiology tools, in vivo brain imaging, and animal behavioral studies.

Individuals with experience or interest in these research areas, who are self-motivated and have a passion for ASD research are encouraged to apply. Applicants are encouraged to view the recent publications and related review papers of Dr. Lee who trained with Dr. Lily Jan at University of California San Francisco (UCSF). Our recent study has been published in Nature Biomedical Engineering (2018, 2: 497-507). [Featured in over 90 news stories, including Nature Research Highlights, Nature Review Materials Research Highlights, and Nature Review Genetics Highlights.] Funding is in place for this position to begin immediately.

A postdoctoral fellowship position is available in the Lee Lab for a candidate with experience in the following areas:
1. Molecular/cellular biology/rodent behaviors in any area OR
2. Neuroscience using rodent models

A postdoctoral fellowship trainee will be trained in the topics they are interested in related to ASD, including:
1) Using gene editing techniques and participating in gene editing therapeutic development
2) Studying the effect of inflammation in ASD using mouse models
3) Studying neurodevelopmental deficits focused on primary cilia deficits

To apply, please send a curriculum vitae (CV), a brief (<2 page) statement of research interests (cover letter), and contact information for three references to Dr. Hye Young Lee at leeh6@uthscsa.edu. The review process will begin immediately.

Please find news about Lee lab at
Lee lab at UTHSCSA: https://physiology.UT Health San Antonio.edu/team-member/hye-young-lee-ph-d/
Lee lab webpage: https://www.hyeyoungleelab.org/news
Applicants are encouraged to check these publications from the Lee Lab:
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1. Nature Biomedical Engineering (2018) Title: Nanoparticle delivery of CRISPR into the brain rescues increased repetitive behaviors in the mouse model of fragile X syndrome. [This paper was featured in over 90 news stories]
2. Stem Cell Reports (2020) Title: Primary Ciliary Deficits in the Dentate Gyrus of Fragile X Syndrome.
3. Scientific Reports (2020) Title: The mouse model of fragile X syndrome exhibits deficits in contagious itch behavior.
All postdoctoral appointments are designated as security sensitive positions. The University of Texas Health Science Center at San Antonio is an Equal Employment Opportunity/Affirmative Action Employer, including protected veterans and persons with disabilities.

All postdoctoral appointments are designated as security sensitive positions. UT Health San Antonio is an Equal Employment Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities.

Postdoctoral Fellowship Neurotransmitter Transporters in Psychiatric Disorders and Addiction 

The Daws Laboratory in the Department of Cellular and Integrative Physiology at the University of Texas Health Science Center at San Antonio (UTHSCSA) is seeking a highly motivated and creative Postdoctoral Fellow to conduct innovative NIDA- and NIMH-funded research on the role of monoamine transporters in substance use disorders, and the circuitry of emotional behavior. Current research is focused on:

1. Investigating organic cation transporter 3 (OCT3) as a novel target for the treatment of psychostimulant disorders.
2. Understanding the role of OCT3 and the serotonin transporter (SERT) in circuits driving fear conditioned behavior.

Through this fellowship, the selected candidate will gain expertise in a variety of techniques, including in vivo electrochemistry, optogenetics, shRNA knockdown, tamoxifen-inducible OCT3 and SERT knockdown, and behavioral techniques, including conditioned place preference, and fear conditioning. The selected candidate will be encouraged to develop an independent line of research. Additional structured opportunities for scientific and career development are provided by a NIDA-funded T32 training grant.

Eligibility: Candidates should have a recent doctoral degree in Neuroscience, Pharmacology, or a related discipline, and a strong interest in conducting drug abuse and/or mental health research. Prior experience with rodents is preferred.

To apply: Send a CV, a brief statement of research/training goals, and the names and contact information of three references to Lynette C. Daws, Ph.D. (daws@uthscsa.edu). Review of applications will begin immediately and continue until the position is filled.

All Postdoctoral appointments are designated as security sensitive positions.
The University of Texas Health San Antonio is an Equal Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities

Postdoctoral Opportunities in CNS Circuits and Metabolism Biology During Brain Repair

Overview. The Department of Cellular and Integrative Physiology in the Long School of Medicine at the University of Texas Health San Antonio is seeking highly motivated postdoctoral fellows to engage in ongoing studies dedicated to the intersection between CNS circuits and metabolism biology during brain repair. Our current efforts test how metabolic co-morbidities of stroke impact long-term behavioral and cellular stroke recovery. This research uses the corticospinal motor system as model cellular pathway to better understand patterns of cellular disruption and adaptation after stroke. We seek to evaluate brain recovery in an integrative fashion by testing outcomes at the level of individual cell, cell network, and whole-animal physiology and behavior. The overall goal of these endeavors is to identify novel therapeutic targets and strategies that provide meaningful long-term behavioral improvement after brain insults including stroke.

Qualifications. Applicants should have a PhD and/or MD in neuroscience or related fields. Applicants who anticipate to defend their thesis in the near future are also encouraged to apply. We are seeking individuals with a demonstrated record of careful experimental methods, high-quality publications, excellent written and communication skills and an ability to design and perform research in an independent manner. Experience in whole-cell patch clamp electrophysiology, whole animal neurophysiology and behavioral tests is preferred but not required.

Employment Details. Salary is commensurate with experience and accomplishments; starting at NIH pay scale. Additional information regarding our laboratory and scientific interests are at https://lsom.uthscsa.edu/physiology/team-member/jeffery-boychuk-ph-d/ and our Department within UT Health San Antonio at lsom.uthscsa.edu/physiology.

In the email application please include a cover letter that describes research experience and states career goals, CV with publications, and detailed contact information for 3 references to:

Jeffery A Boychuk, Ph.D.
Department of Cellular and Integrative Physiology
UT Health San Antonio 78229
Email: BOYCHUK@uthscsa.edu

All Postdoctoral appointments are designated as security sensitive positions.
The University of Texas Health San Antonio is an Equal Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities

Postdoctoral Positions:

The Department of Cellular and Integrative Physiology in the Long School of Medicine at the University of Texas Health San Antonio is seeking highly motivated postdoctoral fellows to engage in NIH-funded ongoing studies related to endocannabinoid signaling in synaptic plasticity and learning and memory as well as in neurodegenerative diseases in Dr. Chen’s laboratory. Specifically, the current research projects in his laboratory are focusing on defining the
mechanisms of neurodegenerative diseases, including Alzheimer’s disease (AD) and traumatic brain injury (TBI)-induced AD-like disease, and identifying novel therapeutic targets for these neurodegenerative diseases. Dr. Chen’s laboratory employs a variety of approaches, including molecular biology, epigenetics, electrophysiological recordings, fluorescent and laser imaging, LC-MS-MS mass spectrometry, and behavioral tests, to elucidate cellular, molecular, and epigenetic mechanisms underlying pathogenesis and neuropathology of AD and TBI-induced ADlike neuropathology. We have a highly interactive and dynamic research environment, and encourage collaborations with colleagues across disciplines. Applicants should have a PhD and/or MD in neuroscience or related fields. We are seeking applicants with experience in epigenetics, bioinformatics, molecular cloning, and in vivo Ca2+ imaging and optogenetics. We are particularly interested in applicants with research experience in studying neuron-glia and/or astrocyte-microglia interactions.

Salary is commensurate with experience and accomplishments. Additional information regarding Dr. Chen’s laboratory and scientific interests are at https://lsom.uthscsa.edu/physiology/teammember/chu-chen-ph-d/ and our Department and the UT Health San Antonio at https://lsom.uthscsa.edu/physiology/

Interested individuals should forward CV along with the names and email addresses of three references to:
Chu Chen, Ph.D.
Department of Cellular and Integrative Physiology
UT Health San Antonio 78229
Email: chenc7@uthscsa.edu

All Postdoctoral appointments are designated as security sensitive positions. The University of Texas Health San Antonio is an Equal Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities.

Highly Motivated Postdoctoral Fellows

The Department of Cellular and Integrative Physiology in the Long School of Medicine at the University of Texas Health San Antonio is seeking highly motivated postdoctoral fellows to engage in ongoing studies related to neuron‐glia interactions underlying axonal domain organization, synapse organization and neural circuitry in genetic model systems. We are particularly interested in elucidating the molecular basis of myelin‐related pathologies and neurodevelopmental disorders emerging from synaptic abnormalities. We have a highly interactive and dynamic research environment, and encourage collaborations with colleagues across disciplines. Applicants with a Ph.D. and demonstrated record of high quality publications, excellent written and communication skills and ability to design and perform research in an independent manner should apply. Experience in mouse or fly genetics, cell biology and/or biochemistry would be most suitable for our many ongoing projects.

Salary is commensurate with experience and accomplishments; starting at NIH pay scale.
Additional information regarding our laboratory and scientific interests are at
www.bhatlab.org and our Department and the UT Health San Antonio at https://lsom.uthscsa.edu/physiology/

To apply, email a single pdf file with a cover letter stating career goals, CV with publications, a description of research experience and detailed contact information for three references to:

Manzoor Bhat, M.S., Ph.D.
Department of Cellular and Integrative Physiology
UT Health San Antonio 78229
Email: bhatm@uthscsa.edu

All Postdoctoral appointments are designated as security sensitive positions. The University of Texas Health San Antonio is an Equal Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities.