DepartmentCellular and Integrative Physiology
IBMS Physiology and Pharmacology Discipline
Dr. Andrew Brenner, M.D., Ph.D.
Hobbies & Interests:
Exploring places, rafting, numismatics, philately, notaphily, reading transcendental philosophy and biographical accounts.
MD from Institute of Medical Sciences, Bhubaneswar, India
Diploma in Emergency Medicine (DEM) at Apollo Hospital Educational and Research Foundations, Kolkata, India, affiliated to the Royal College of General Practitioners, UK (RCGP, UK)
Bachelor of Medicine and Bachelor of Surgery (MBBS) from Vydehi Institute of Medical Sciences and Research Centre, Bangalore, India
Research on Glioblastoma multiforme (GBM) is challenging due to the intractable course of the tumor and high mortality in patients. Despite the implementation of various combinations of treatment modalities (surgery, chemotherapy, adjuvant chemotherapy), the survival rate for patients stands low. Targeting angiogenesis with anti-angiogenic treatments such as Bevacizumab in GBM was considered a golden approach, until preclinical data revealed the tumor to evade the angiogenesis machinery and rely on fatty acid from the surrounding to receive ATP. My research focus is to explore this adaptive tumoral response to hypoxia and develop suitable therapeutics to overcome treatment resistance.
Bhattacharya A, Ashouri R, Fangman M, Mazur A, Garett T, Doré S. Soluble Receptors Affecting Stroke Outcomes: Potential Biomarkers and Therapeutic Tools. Int J Mol Sci. 2021 Jan 23;22(3):1108. doi: 10.3390/ijms22031108. PMID: 33498620; PMCID: PMC7865279.
Robicsek SA*, Bhattacharya A*, Rabai F*, Shukla K, Doré S. Blood-related toxicity after TBI: Potential targets for neuroprotection. Molecular Neurobiology (2019). DOI: 10.1007/s12035-019-01766-8. [PMID: 31617072]
Bhattacharya A, Tiwari P, Sahu PK, Kumar S. A Review of the Phytochemical and Pharmacological Characteristics of Moringa Oleifera. J Pharm Bioall Sci 2018; 10:181-91. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266645/) [PUBMED] [PMID: 30568375]
Rath, M, Bhattacharya A, Rath K, Santra S, Ghosh G, Nanda B. (2020). A Comprehensive Study of the Neuropharmacological Profile of Methanol Leaf Extract of Aloe vera and Identification of Associated Neuroprotective Compounds through Gas chromatography-mass spectrometry Analysis. Indian Journal of Pharmaceutical Sciences. 2020;82(6):996-1005. https://www.ijpsonline.com/articles/a-comprehensive-study-of-the-neuropharmacological-profile-of-methanol-leaf-extract-of-aloe-vera-and-identification-of-associated-n-4052.html
Rath M, Bhattacharya A, Santra S, Rath K, Ghosh G, Nanda BB. Neuro-pharmacological Effects of Methanolic Extract of Clerodendrum Viscosum Leaves on Wistar Albino Rats. Phcog Mag, 2018;14:507-14 (http://www.phcog.com/article.asp?issn=0973-1296;year=2018;volume=14;issue=59;spage=507;epage=514;aulast=Rath)
Ayon Bhattacharya, Divya Agrawal, Pratap Kumar Sahu, Sanjay Kumar, Sudhanshu S. Mishra, Shantilata Patnaik. Analgesic Effect of Ethanolic Leaf Extract of Moringa Oleifera on Albino Rats. Indian Journal of Pain, 2014; 28:89-94 (http://www.indianjpain.org/text.asp?2014/28/2/89/132846 )
Santra S, Bhattacharya A, Mukhopadhyay T, Agrawal D, Kumar S, Das P, Chakraborty P. Use of Iron Chelating Agents in Transfusion Dependent Thallasemia Major Patients. Mymensingh Med J. 2015; 24(4):838-844 (http://www.ncbi.nlm.nih.gov/pubmed/26620028 ). [PUBMED] [PMID: 26620028]
Manas Ranjan Naik, Ayon Bhattacharya, Rasmirekha Behera, Divya Agrawal, Suhasini Dehury, Sanjay Kumar. Study of Anti-Inflammatory Effect of Neem Seed Oil (Azadirachta indica) on Infected Albino Rats. Journal of Health Research and Reviews. 2014; 1:66-69 (http://www.jhrr.org/text.asp?2014/1/3/66/153880 )