DepartmentCellular and Integrative Physiology
Hye Young Lee, Ph.D
B.S., Biological Sciences, Ewha Women's University
Ph.D., Life Science, Pohang University of Science and Technology
Dr. Lee’s research focus is on studying the pathophysiological mechanisms underlying autism spectrum disorders (ASD). Autism spectrum disorders (ASD) form a heterogeneous neurodevelopmental syndrome characterized by deficits in language development/social interactions, and repetitive behavior/restricted interests. ASD likely arises from a complex combination of risk factors. However, it remains possible that certain aspects of the molecular pathophysiology responsible for ASD are recurrent themes that can inform the underlying neurobiological basis of ASD.
The Lee lab focuses on:
1) Identifying the molecular mechanisms responsible for the pathophysiology of autism and related disorders, and using these mechanisms to rescue behavioral dysfunction in mouse models
2) Elucidating specific autistic behaviors including social communication deficits and repetitive behaviors, and identifying the brain region(s) and neuron groups underlying these behavioral deficits in mouse models. To address these questions, Dr. Lee uses molecular and cellular neurobiology tools, in vivo brain imaging, and animal behavioral studies.
Jennifer Michelle Parrott, Ph.D.
Devendra Kumar, Ph.D.
Jan Tuma, Ph.D.
Anshuman Sinha, Ph.D.
Rodrigo Rojas-Gonzalez (former NISD and SRD student)
Amtul-noor Rana (former SRD Student)
Srilalitha Lanka (former NISD Student)
Izumi Vazquez (Current NISD student)
High School Student:
Laura Beuhler (current Voelcker Student)
Shreya Kommera (current MRP Student)
Former Lab Members:
Isabel Moh (former Undergraduate Student)
Peter Mason (former Voelcker student)
Anagha Kolanu (former NISD Student)
Please find news about Lee lab at www.hyeyoungleelab.org/news/
Please check recent publications from Lee lab at https://www.ncbi.nlm.nih.gov/myncbi/1DCUx12nLD_oK4/bibliography/public