COPD

Patients with COPD are seen throughout several UT Health San Antonio pulmonary clinics. Our center has been part of the NHLBI funded COPDGene® project since 2007. The Pulmonary division includes two COPD nationally/internationally recognized COPD experts, Dr. Antonio Anzueto and Dr. Sandra Adams.  Dr. Anzueto has contributed to numerous COPD trials and regularly participates in the annual revision of international Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations. Dr. Adams leads local and national COPD educational initiatives and is the founder of the WipeDiseases Foundation which educates patients, caregivers, and healthcare professionals about COPD and asthma to improve patient outcomes and to promote lifelong learning. Patients have access to state-of-the-art treatments including optimal bronchodilators, biological therapy, and invasive interventional procedures.

Selected publications

  • Anzueto A, Barjaktarevic IZ, Siler TM, Rheault T, Bengtsson T, Rickard K, Sciurba F. Ensifentrine, a Novel Phosphodiesterase 3 and 4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease: Randomized, Double-Blind, Placebo-controlled, Multicenter Phase III Trials (the ENHANCE Trials). Am J Respir Crit Care Med. 2023 Aug 15;208(4):406-416. doi: 10.1164/rccm.202306-0944OC. PMID: 37364283; PMCID: PMC10449067.
  • Sin DD, Doiron D, Agusti A, Anzueto A, Barnes PJ, Celli BR, Criner GJ, Halpin D, Han MK, Martinez FJ, Montes de Oca M, Papi A, Pavord I, Roche N, Singh D, Stockley R, Lopez Varlera MV, Wedzicha J, Vogelmeier C, Bourbeau J; GOLD Scientific Committee. Air pollution and COPD: GOLD 2023 committee report. Eur Respir J. 2023 May 11;61(5):2202469. doi: 10.1183/13993003.02469-2022. PMID: 36958741.
  • Agustí A, Celli BR, Criner GJ, Halpin D, Anzueto A, Barnes P, Bourbeau J, Han MK, Martinez FJ, Montes de Oca M, Mortimer K, Papi A, Pavord I, Roche N, Salvi S, Sin DD, Singh D, Stockley R, López Varela MV, Wedzicha JA, Vogelmeier CF. Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. Eur Respir J. 2023 Apr 1;61(4):2300239. doi: 10.1183/13993003.00239-2023. PMID: 36858443; PMCID: PMC10066569.
  • Adams SG, Estrada RA. Is Age Just a “Number” When Evaluating the Efficacy and Safety of Triple-Inhaled Therapy in COPD? Chest. 2021 Mar;159(3):895-896. doi: 10.1016/j.chest.2020.10.022. PMID: 33678268.
  • Halpin DMG, Criner GJ, Papi A, Singh D, Anzueto A, Martinez FJ, Agusti AA, Vogelmeier CF. Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. The 2020 GOLD Science Committee Report on COVID-19 and Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2021 Jan 1;203(1):24-36. doi: 10.1164/rccm.202009-3533SO. PMID: 33146552; PMCID: PMC7781116.
  • Maselli DJ, Bhatt SP, Anzueto A, Bowler RP, DeMeo DL, Diaz AA, Dransfield MT, Fawzy A, Foreman MG, Hanania NA, Hersh CP, Kim V, Kinney GL, Putcha N, Wan ES, Wells JM, Westney GE, Young KA, Silverman EK, Han MK, Make BJ. Clinical Epidemiology of COPD: Insights From 10 Years of the COPDGene Study. Chest. 2019 Aug;156(2):228-238. doi: 10.1016/j.chest.2019.04.135. Epub 2019 May 30. PMID: 31154041; PMCID: PMC7198872.
  • Maselli DJ, Hardin M, Christenson SA, Hanania NA, Hersh CP, Adams SG, Anzueto A, Peters JI, Han MK, Martinez FJ. Clinical Approach to the Therapy of Asthma-COPD Overlap. Chest. 2019 Jan;155(1):168-177. doi: 10.1016/j.chest.2018.07.028. Epub 2018 Aug 2. PMID: 30077690; PMCID: PMC6688980.
  • Anzueto A, Miravitlles M. Pathophysiology of dyspnea in COPD. Postgrad Med. 2017 Apr;129(3):366-374. doi: 10.1080/00325481.2017.1301190. Epub 2017 Mar 17. PMID: 28277858.
  • Amalakuhan B, Adams SG. Improving outcomes in chronic obstructive pulmonary disease: the role of the interprofessional approach. Int J Chron Obstruct Pulmon Dis. 2015 Jun 26;10:1225-32. doi: 10.2147/COPD.S71450. PMID: 26170651; PMCID: PMC4492629.
  • Hurst JR, Vestbo J, Anzueto A, Locantore N, Müllerova H, Tal-Singer R, Miller B, Lomas DA, Agusti A, Macnee W, Calverley P, Rennard S, Wouters EF, Wedzicha JA; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med. 2010 Sep 16;363(12):1128-38. doi: 10.1056/NEJMoa0909883. PMID: 20843247.