Colorectal cancer screening utilizing a Fecal Immunochemical Testing (FIT) sampling method is a common practice in Primary Care. Previous research has shown that approximately 6.2% of screening fecal immunochemical tests (FIT) results are positive, with a positive predictive value (PPV) of 35% to 55%. However, many patients use oral anticoagulants (OACs) and NSAIDs that may stimulate bleeding from benign and premalignant colon lesions. This discussion will look into whether the use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), and oral anticoagulants reduce the PPV by making benign lesions more likely to bleed (leading to more false-positive results), or whether it increases the PPV by making precancerous and malignant lesions more likely to bleed.


1. Define current available colon cancer screening methods, with a focus on stool-based testing.

2. Discuss effects of OACs and NSAIDs on FIT performance as described in systematic review.

3.  Identify suggested approaches for the use of OACs and NSAIDs prior to FIT screening in primary care setting.

About the Speaker(s):

Chi Stasio, OD

Chi Stasio, DO
PGY-3 Resident
Department of Family and Community Medicine
UT Health San Antonio

Financial Disclosures:

Chi Stasio, DO and her faculty mentor, Miguel Palacios, MD have no relevant financial relationships with commercial interests to disclose.

The Family & Community Medicine Professional Development and Grand Rounds Committee members (Mark Nadeau, MD, Marcy Wiemers, MD, Maria Del Pilar Montañez Villacampa, MD, Christine Song, DO, Nehman Andry, MD, Margaret Finley, MD, Andrew Dinh, DO, Maureen Alvarado, DO, Richel Avery, MD, Inez I. Cruz, PhD, and Nichole Rubio) have no relevant financial relationships to commercial interests to disclose.

The Family & Community Medicine Professional Development and Grand Rounds Committee member Carlos Roberto Jaén, MD has disclosed he receives royalties from General Practice and Family Medicine for being UpToDate Editor-in-Chief.


AMA PRA Category 1 Credits™ (1.00 hours), Non-Physician Participation Credit (1.00 hours)

Target Audience:

Specialties – Primary Care; Family Medicine
Faculty, residents, other health care providers and staff from our department; physicians and health care providers from San Antonio and South Texas; and medical students in our third-year clerkship and fourth year rotations.


The UT Health Long San Antonio School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation:

The Long School of Medicine designates this live activity up to a maximum of 1.00 AMA PRA Category 1 Credits™.

Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses and other healthcare professionals will receive a Certificate of Attendance. For information on applicability and acceptance, please consult your professional licensing board.

View Recording (CME Credit)

View Recording (no CME Credit)

For activity related questions, please contact:
Name: Nichole Rubio- FCM Grand Rounds Coordinator
Email: rubion@uthscsa.edu

For CME general questions, please contact
Ph: (210) 567-4445
Email: cme@uthscsa.edu