New publication alert on the Kidney-Brain axis!
Led by our PhD graduate, Dr. Afaf Saliba, under the mentorship of our director Dr. Kumar Sharma!
https://insight.jci.org/articles/view/180229
This research highlights a crucial connection between kidney disease and brain health. The team found that quinolinic acid, a byproduct of tryptophan metabolism, builds up in the plasma kidney and brain during kidney failure, associated with inflammation and potential damage.
These insights open new possibilities for better diagnosing and understanding of neurological complications in kidney disease.
Congratulations to Dr. Saliba and the multidisciplinary teams for this valuable contribution!
Authors: Afaf Saliba, Subrata Debnath, Ian Tamayo, Hak Joo Lee, NAGARJUNACHARY RAGI, Falguni Das, Richard Montellano, Jana Tumova, Meyer Maddox, Esmeralda Trevino, Pragya Singh, Ph.D., Caitlyn Fastenau, Soumya Maity, Guanshi Zhang, Leila Hejazi, Manjeri A. Venkatachalam, Jason C. O’Connor, Bernard Fongang, Sarah Hopp, Kevin F. Bieniek, Ph.D., Jim Lechleiter , Ph D., Kumar Sharma, MD
