Posts written by spillmanne

David Kadosh, PhD receives R21 award

January 30, 2023

David Kadosh, PhD received an R21 award entitled Translational Regulation of Candida glabrata Azole Resistance.  This two-year grant began January 20, 2023.  Congratulations, Dr. Kadosh!

Nu Zhang, PhD receives VA Merit Award

January 30, 2023

Dr. Nu Zhang received a 4-year VA Merit award entitled Targeting lymphoid tissue residency to boost tumor immunotherapies starting in January 2023.  Congratulations, Dr. Zhang!

UT Health San Antonio, Ohio company reach license agreement to develop chlamydia vaccine

December 16, 2022

UT Health San Antonio, Ohio company reach license agreement to develop chlamydia vaccine Wed, December 14, 2022 at 1:00 PM SAN ANTONIO, Texas, Dec. 14, 2022 /PRNewswire-PRWeb/ — The University of Texas Health Science Center at San Antonio has granted an exclusive global license allowing an Ohio biopharmaceutical company to develop university research discoveries into a novel oral vaccine for chlamydia. According to […]

MIMG Pilot Projects Awarded

December 16, 2022

Congratulations to our MIMG faculty members who were awarded Pilot Projects for the year! Zhenming Xu (PI) and David Kadosh (Co-PI) were awarded an MIMG Pilot Project FY22-23 entitled: Interaction of B regulatory cells and commensal Candida albicans in the maintenance of gut homeostasis. Evelien Bunnik (PI) and Ian Cheeseman (Co-PI) were awarded an MIMG […]

Dr. Zhang profile photo

Nu Zhang, PhD publishes paper in Nature Communications

October 13, 2022

Congratulations to Nu Zhang, Ph.D. and his lab for his new publication, “TGF-b-dependent lymphoid tissue residency of stem-like T cells limits response to tumor vaccine.” published in Nature Communications. In this paper, they report that stem-like CD8+ T cells differentiate into tissue-resident cells inside tumor draining lymph nodes. This differentiation program inhibits tumor vaccine induced […]

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Ann Griffith, PhD and her trainees publish article in PNAS

October 4, 2022

Congratulations to Dr. Ann Griffith and her trainees for their paper showing that oxidative stress is not always bad.  It is required by thymic stromal cells for the clonal deletion of autoreactive T Cells. From the article: Thymic stromal cells impose T cell self-tolerance by presenting self-antigens to developing T cells and inducing apoptosis in […]

Ann Griffith, PhD and Na Xiong, PhD publish paper in Journal of Immunology

August 31, 2022

Congratulations to Dr. Griffith and Dr. Xiong for their Journal of Immunology publication, Delta-like 4–Derived Notch Signals Differentially Regulate Thymic Generation of Skin-Homing CCR10+NK1.1+ Innate Lymphoid Cells at Neonatal and Adult Stages The thymus is a primary lymphoid organ for T cell development. Increasing evidence found that the thymus is also an important site for […]

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Elizabeth Leadbetter, PhD publishes paper in Cell Metabolism

August 23, 2022

Congratulations to Dr. Elizabeth Leadbetter for her recently published paper in Cell Metabolism! Obesity is accompanied by inflammation in adipose tissue, impaired glucose tolerance, and changes in adipose leukocyte populations. These studies of adipose tissue from humans and mice revealed that increased frequencies of T-bet+ B cells in adipose tissue depend on invariant NKT cells […]

Paolo Casali, M.D. publishes paper in Nature Communications

August 23, 2022

Congratulations to Paolo Casali, MD for this paper recently published in Nature Communications. Summarized in Dr. Casali’s own words: This paper reports the first “discovery” of the mechanism of class-switch DNA recombination to IgD (by microhomology-mediated DNA end-joining, very different from CSR to IgG, IgA or IgE (by non-homologous DNA end-joining), as well as the […]