Publications and Presentations

Susan R. Rose, Ari J. Wassner, Kupper A. Wintergerst, Nana-Hawa Yayah-Jones, Robert J. Hopkin, Janet Chuang, Jessica R. Smith, Katherine Abell, Stephen H. LaFranchi, SECTION ON ENDOCRINOLOGY EXECUTIVE COMMITTEE, COUNCIL ON GENETICS EXECUTIVE COMMITTEE; Congenital Hypothyroidism: Screening and Management. Pediatrics January 2023; 151 (1): e2022060420. 10.1542/peds.2022-060420 PMID: 36827523

Castellanos LE, Russell SJ, Damiano ER, Beck RW, Shah VN, Bailey R, Calhoun P, Bird K, Mauras N; Bionic Pancreas Research Group. The Insulin-Only Bionic Pancreas Improves Glycemic Control in Non-Hispanic White and Minority Adults and Children With Type 1 Diabetes. Diabetes Care. 2023 Mar 31:dc221478. doi: 10.2337/dc22-1478. Epub ahead of print. PMID: 37000680.

Mauras N, Damiano ER, El-Khatib FH, Marak MC, Calhoun P, Ruedy KJ, Balliro C, Li Z, Beck RW, Russell SJ. Utility and Safety of Backup Insulin Regimens Generated by the Bionic Pancreas: A Randomized Study. Diabetes Technol Ther. 2023 Mar 22. doi: 10.1089/dia.2022.0461. Epub ahead of print. PMID: 36877259.

Francis GL. Macro–Thyrotropin and Other Disorders in the Differential Diagnosis of Congenital Hypothyroidism. Clinical Thyroidology 2023 Feb; 132(11) 142–146. Published Online:11 April 2023.

J. Carey; J. Cody, J. Mehl; J. Gelfond. Causes of death and associated factors in patients with trisomy 18 syndrome and long-term survival. Volume 1, Issue 1, Supplement, 100167, 2023. Genetics of Medicine Open. https://doi.org/10.1016/j.gimo.2023.100167

Jill Weissberg-Benchell, PhD¹; Anthony T. Vesco, PhD¹; Jenna Shapiro, PhD¹; Peter Calhoun, PhD²; Edward R. Damiano, PhD^3,4; Steven J. Russell, MD, PhD⁴; Zoey Li, MS²; Firas H. El-Khatib, PhD⁴; Katrina J. Ruedy, MSPH²; Courtney A. Balliro, RN⁴; Roy W. Beck, MD, PhD²; and the Bionic Pancreas Research Group*, Psychosocial Impact of the Insulin-Only iLet Bionic Pancreas for Adults, Youth, and Caregivers of Youth with Type 1 Diabetes, (In press)

Lynch J, Hughan K, Kutney K, Tollefsen S;Uschner D, Laffel, L, Haymond, M, Escaname, E, Wen W. Trajectories of eGFR and risk of albuminuria in youth with T2D: results from the TODAY cohort study.  Pediatric Nephrology (In press)

Francis GL. Thyroid Function Abnormalities in Childhood Cancer Survivors. Clinical Thyroidology 2023 Apr (in press)

Messer LH, Buckingham BA, Cogen F, Daniels M, Forlenza G, Jafri RZ, Mauras N, Muir A, Wadwa RP, White PC, Russell SJ, Damiano ER, El-Khatib FH, Ruedy KJ, Balliro CA, Li Z, Marak MC, Calhoun P, Beck RW. Positive Impact of the Bionic Pancreas on Diabetes Control in Youth 6-17 Years Old with Type 1 Diabetes: A Multicenter Randomized Trial. Diabetes Technol Ther. 2022 Oct;24(10):712-725. doi: 10.1089/dia.2022.0201.pub. PMID: 36173237; PMCID: PMC9529304.

Lynch J, Kanapka LG, Russell SJ, Damiano ER, El-Khatib FH, Ruedy KJ, Balliro C, Calhoun P, Beck RW. The Insulin-Only Bionic Pancreas Pivotal Trial Extension Study: A Multi-Center Single-Arm Evaluation of the Insulin-Only Configuration of the Bionic Pancreas in Adults and Youth with Type 1 Diabetes. Diabetes Technol Ther. 2022 Oct;24(10):726-736. doi: 10.1089/dia.2022.0341. PMID: 36173238; PMCID: PMC9529297.

Beck RW, Russell SJ, Damiano ER, El-Khatib FH, Ruedy KJ, Balliro C, Li Z, Calhoun P. A Multicenter Randomized Trial Evaluating Fast-Acting Insulin As part in the Bionic Pancreas in Adults with Type 1 Diabetes. Diabetes Technol Ther. 2022 Oct;24(10):681-696. doi: 10.1089/dia.2022.0167. PMID: 36173235; PMCID: PMC9529301.

Bionic Pancreas Research Group, Russell SJ, Beck RW, Damiano ER, El-Khatib FH, Ruedy KJ, Balliro CA, Li Z, Calhoun P, Wadwa RP, Buckingham B, Zhou K, Daniels M, Raskin P, White PC, Lynch J, Pettus J, Hirsch IB, Goland R, Buse JB, Kruger D, Mauras N, Muir A, McGill JB, Cogen F, Weissberg-Benchell J, Sherwood JS, Castellanos LE, Hillard MA, Tuffaha M, Putman MS, Sands MY, Forlenza G, Slover R, Messer LH, Cobry E, Shah VN, Polsky S, Lal R, Ekhlaspour L, Hughes MS, Basina M, Hatipoglu B, Olansky L, Bhangoo A, Forghani N, Kashmiri H, Sutton F, Choudhary A, Penn J, Jafri R, Rayas M, Escaname E, Kerr C, Favela-Prezas R, Boeder S, Trikudanathan S, Williams KM, Leibel N, Kirkman MS, Bergamo K, Klein KR, Dostou JM, Machineni S, Young LA, Diner JC, Bhan A, Jones JK, Benson M, Bird K, Englert K, Permuy J, Cossen K, Felner E, Salam M, Silverstein JM, Adamson S, Cedeno A, Meighan S, Dauber A. Multicenter, Randomized Trial of a Bionic Pancreas in Type 1 Diabetes. N Engl J Med. 2022 Sep 29;387(13):1161-1172. doi: 10.1056/NEJMoa2205225. PMID: 36170500.

Gandica R, Weinstock RS, Gunaratne M, Arslanian S, Doherty L, Geffner ME, Laffel L, Higgins J; TODAY Study Group. Long-Term Retention of Young Adult Study Participants with Youth-Onset Type 2 Diabetes: Results from the TODAY2 Study. Horm Res Paediatr. 2023;96(3):325-331. doi: 10.1159/000528205. Epub 2022 Nov 21. PMID: 36412631.

TODAY Study Group. Long-term Outcomes Among Young Adults With Type 2 Diabetes Based on Durability of Glycemic Control: Results From the TODAY Cohort Study. Diabetes Care. 2022 Nov 1;45(11):2689-2697. doi: 10.2337/dc22-0784. PMID: 36190810; PMCID: PMC9679266.

Levitsky LL, Drews KL, Haymond M, Glubitosi-Klug RA, Levitt Katz LE, Mititelu M, Tamborlane W, Tryggestad JB, Weinstock RS; TODAY Study Group. The obesity paradox: Retinopathy, obesity, and circulating risk markers in youth with type 2 diabetes in the TODAY Study. J Diabetes Complications. 2022 Nov;36(11):108259. doi: 10.1016/j.jdiacomp.2022.108259. Epub 2022 Jul 19. PMID: 36150365.

Mittileu M, Uschner D, Doherty L, Bjornstad P, Domalpally A, Drews KL, Gubitosi-Klug R, Levitsky LL, Pak JW, White NJ, Blodi BA, TODAY Study Group. Retinal Thickness and Morphology Changes on OCT in Youth with Type 2 Diabetes.  Findings from the TODAY Study.  Ophthalmol Sci. 2022 Jun 28;2(4):100191. doi: 10.1016/j.xops.2022.100191. eCollection 2022 Dec. PMID: 36531589.

Luisa Rodriguez, MD, MS1, Catherine Dinauer, MD2, Gary Francis, MD, PhD3. Treatment of Hypothyroidism in Infants, Children and Adolescents. Trends in Endocrinology and Metabolism, VOLUME 33, ISSUE 7, P522-532, JULY 01, 2022. PMID: 35537910

Catherine E. Kerr, MD1; Jorge Velez, MD2; Jay Ferrell, MD3; Mio Kitano, MD4; Dr. Wouter Koek, PhD5; Patricia Dahia, MD, PhD6; and Gary Francis, MD, PhD1. Thyroid Nodules of Indeterminate Cytology in Hispanic/Latinx Patients. Head and Neck, 2022 Aug;44(8):1842-1848. PMID: 35583054.

Francis, GL. Review of: Bardugo A, Derazne E, Zucker I, Bendor C, Puris G, Lutski M, Pinhas-Hamiel O, Cukierman-Yaffe T, MosenzonO\ O, Schechter M, Tzur D, Afek A, Tirosh A, Gerstein H, Raz I, and Twig G 2021. Adolescent Thyroid Disorders and Risk for Type 2 Diabetes in Young Adult. J Clin Endocrinol Metab 106:e3426-e3435 Adolescent Thyroid Disease and Risk for Adult Type 2 Diabetes. Clinical Thyroidology 34 (1) 6-9, 2022. PMID: 34050759

Francis, GL. What’s the Likelihood of Post-Lobectomy Hypothyroidism in Children? Clinical Thyroidology 34(3) 100-102, 2022. https://doi.org/10.1089/ct.2022;34.100-102. PMID: 19789012

Francis, GL. The Future of Molecular Profiling for the Treatment of Pediatric Thyroid Cancer. Review of: NTRK and RET fusion–directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake. J Clin Invest. 131(18):e144847  https://doi.org/10.1172/JCI144847. Clinical Thyroidology, 34(4)2022:157-160. PMID: 34237031

Francis GL. Screening for Neonatal Hyperthyroidism. A review of: Banigé M, Kariyawasam D, Gauthereau V, Luton D, Polak M 2022 Neonatal Screening for Hyperthyroidism Proof of Concept. J Clin Endocrinol Metab Mar 24;107(4):e1374-e1381. doi: 10.1210/clinem/dgab890. Clinical Thyroidology 34:282-285, 2022. PMID: 34894265

Francis GL. Trends in Lobectomy for Pediatric Thyroid Cancer. A review of: Eli Stein BS, Mehul V. Raval MD, MS, Inbal Hazkani MD, Audra Reiter MD, MPH, Jami L. Josefson MD, Jill H. Samis MD, and Jeffrey C. Rastatter MD, MS. The 2015 American Thyroid Association guidelines and trends in hemithyroidectomy utilization for pediatric thyroid cancer. Head & Neck. 2022;44:1833–1841. Clinical Thyroidology 34(8) 347-350, 2022.

Francis GL. Trends in Pediatric and Adult Iodine Status in the United States. Review of: Zhang K, Cheng J, Yu J, Chen Y, Shi X, Zhu C, Lu Y, Wang N, Han B 2022 Trends in iodine status among U.S. children and adults: A cross-sectional analysis of National Health and Nutrition Examination Survey data from 2001–2004 to 2017–2020. Thyroid 32:962–971. PMID: 35822552. Clinical Thyroidology 34(11) 2022.

Francis GL. Maternal Thyroid Autoimmunity Affects the Emotional and Behavioral Development of the Offspring. A Review of: Teng Y, Li P, Yang M, Han Y, Yan S, Xu Y, Tao F, Huang K 2022 Sex-specific effect of thyroid peroxidase antibody and thyroglobulin antibody exposure during pregnancy on preschoolers’ emotional and behavioral development: A birth cohort study. Thyroid 32:1229–1242. PMID: 35920111. Clinical Thyroidology 34(12):521-525, 2022.

Francis GL. Inadvertent Parathyroid Gland Removal During Thyroid Surgery in Children. A review of: Ziai H, Dixon P, Berman G, Campisi P, Wasserman JD. 2002 Incidental Parathyroidectomy Among Pediatric Patients Undergoing Thyroid Surgery. Laryngoscope. 2022 Nov;132(11):2262-2269. doi: 10.1002/lary.30056. Epub 2022 Feb 22. PMID: 35191038 Clinical Thyroidology February 2023. PMID: 35191038

Postintervention Effects of Varying Treatment Arms on Glycemic Failure and β-Cell Function in the TODAY Trial. Diabetes Care. 2021 Jan;44(1):75-80. doi: 10.2337/dc20-0622. Epub 2020 Nov 10. PMID: 33290248

Castellanos LE, Balliro CA, Sherwood JS, Jafri R, Hillard MA, Greaux E, Selagamsetty R, Zheng H, El-Khatib FH, Damiano ER, Russell SJ. Performance of the Insulin-Only iLet Bionic Pancreas and the Bihormonal iLet Using Dasiglucagon in Adults With Type 1 Diabetes in a Home-Use Setting. Diabetes Care. 2021 Apr 27:dc201086. doi: 10.2337/dc20-1086. Epub ahead of print. PMID: 33906916.

TODAY Study Group; Bjornstad P, Drews KL, Caprio S, Gubitosi-Klug R, Nathan DM, Tesfaldet B, Tryggestad J, White NH, Zeitler P. Long-Term Complications in Youth-Onset Type 2 Diabetes. N Engl J Med. 2021 Jul 29;385(5):416-426. doi: 10.1056/NEJMoa2100165. PMID: 34320286; PMCID: PMC8697255.

TODAY Study Group. Effects of Metabolic Factors, Race-Ethnicity, and Sex on the Development of Nephropathy in Adolescents and Young Adults With Type 2 Diabetes: Results From the TODAY Study. Diabetes Care. 2021 Sep 16;45(5):1056–64. doi: 10.2337/dc21-1085. Epub ahead of print. PMID: 34531309; PMCID: PMC9174961.

He S, Ryu J, Liu J, Luo H, Lv Y, Langlais PR, Wen J, Dong F, Sun Z, Xia W, Lynch JL, Duggirala R, Nicholson BJ, Zang M, Shi Y, Zhang F, Liu F, Bai J, Dong LQ. LRG1 is an adipokine that mediates obesity-induced hepatosteatosis and insulin resistance. J Clin Invest. 2021 Dec 15;131(24):e148545. doi: 10.1172/JCI148545. PMID: 34730111; PMCID: PMC8670837.

Sherwood JS, Jafri RZ, Balliro CA, Zheng H, FH El-Khatib, ER Damiano, SJ Russell, MS Putman. Automated glycemic control with the bionic pancreas in cystic fibrosis-related diabetes: A pilot study. J Cyst Fibros 2020; Jan;19(1):159-161. doi: 10.1016/j.jcf.2019.08.002. Epub 2019 Aug 13. PMID: 31420176

Bjornstad P, Hughan K, Kelsey MM, Shah AS, Lynch J, Nehus E, Mitsnefes M, Jenkins T, Xu P, Xie C, Inge T, Nadeau K. Effect of Surgical Versus Medical Therapy on Diabetic Kidney Disease Over 5 Years in Severely Obese Adolescents With Type 2 Diabetes. Diabetes Care. 2020 Jan ;43(1):187-195. doi: 10.2337/dc19-0708 Epub 2019 Nov 4. PMID: 31685489 PMCID: PMC6925577

Cody JD. Molecular biology of abnormal gene dosage: lessons from chromosome 18 Trends in Genetics. 2020 Jan PMID: 32660784

Jalaludin MY, Barrientos-Pérez M, Hafez M, Lynch J, Shehadeh N, Turan S, Weghuber D. Recommendations for improving clinical trial design to facilitate the study of youth-onset type 2 diabetes. Clin Trials 2020 Feb;17(1):87-98 doi: 10.1177/1740774519870190. Epub 2019 Aug 26. PMID: 31450961

HE Rizzo, EN Escaname, NB Alana, E Lavender, J Gelfond, R Fernandez, MA Hibbs, JM King, NR Carr, CL Blanco. Maternal Diabetes and obesity influence the fetal epigenome in a largely Hispanic population. Clinical Epigenetics 2020 Feb 19;12(1):34. Doi:10.1186/s13148-020-0824-9. PMID: 32075680

Shah R, McKay SV, Levitt Katz LE, El Ghormli L, Anderson BJ, Casey TL, Higgins L, Izquierdo R, Wauters AD, Chang N; TODAY Study Group.(J Lynch, E Escaname, M Rayas) Adherence to multiple medications in the TODAY (Treatment Options for type 2 Diabetes in Adolescents and Youth) cohort: effect of additional medications on adherence to primary diabetes medication. J Pediatr Endocrinol Metab. 2020 Feb 25;33(2):191-198. doi: 10.1515/jpem-2019-0315. PMID: 31809265.

Catherine Kerr MD, Gary Francis MD PhD. Thyroid Nodules in Children and Adolescents. Journal of Radiology and Imaging Science. J Radiol & Imaging Sci. March 2020;1(1):1-5.

Kaar JL, Schmiege SJ, Drews K, Higgins J, Walders-Abramson N, Isganaitis E, Willi SM, Marcus MD, Zeitler PS, Kelsey MM. Evaluation of the longitudinal change in health behavior profiles across treatment groups in the TODAY clinical trial. (J Lynch, E Escaname, M Rayas) Pediatr Diabetes. 2020 Mar;21(2):224-232. doi: 10.1111/pedi.12976 PMID: 31886931.

MA Van Name, P Cheng, RL Gal, C Kollman, J Lynch, B Nelson, WV Tamborlane, & Pediatric Diabetes Consortium [J Lynch, C Orsi, M Rayas, E Escaname, R Barajas]. Children and adolescents with type 1 and type 2 diabetes mellitus in the Pediatric Diabetes Consortium Registries: comparing clinical characteristics and glycaemic control. Diabetic Medicine 2020 May;37(5), 863-867. Doi:10.1111/dme.14233 Epub 2020 Feb 5. PMID: 31943374

Phillips WT, Kukkar V, Francis GL, Gorzell BC, Cooper AW, Metter DF, LancasterJL. FASpecT/CT, A New SPECT/CT Acquisition With Higher Sensitivity and Efficiency in Radioiodine Thyroid Cancer Imaging. Clin Nucl Med. 2020 May;45(5):356-364. PMID: 32149813.

Sengwee Toh, Sheryl L Rifas-Shiman, Pi-I D Lin, L Charles Bailey, Christopher B Forrest, Casie E Horgan, Douglas Lunsford, Erick Moyneur, Jessica L Sturtevant, Jessica G Young, Jason P Block, PCORnet Antibiotics and Childhood Growth Study Group: Maria Rayas. Privacy-protecting multivariable-adjusted distributed regression analysis for multi-center pediatric study. Pediatr Res 2020 May; 87(6):1086-1092. PMID: 31578038

Jafri R, Balliro C, El-Khatib F, et al. A Three-way Accuracy Comparison of the Dexcom G5, Abbott Freestyle Libre Pro, and Senseonics Eversense CGM Devices in an Home-Use Study of Subjects with Type 1 Diabetes. Diabetes Technol Ther 2020 May 26. doi: 10.1089/dia.2019.0449 Online ahead of print PMID: 32453604

Arslanian S, El Ghormli L, Haymond MH, Chan CL, Chernausek SD, Gandica RG, Gubitosi-Klug R, Levitsky LL, Siska M, Willi SM; TODAY Study Group. (J Lynch, E Escaname, M Rayas) Beta cell function and insulin sensitivity in obese youth with maturity onset diabetes of youth mutations vs type 2 diabetes in TODAY: Longitudinal observations and glycemic failure. Pediatr Diabetes. 2020 Jun;21(4):575-585. doi: 10.1111/pedi.12998. Epub 2020 Mar 3. PMID: 32064729

Kumar, S., Lteif, A., Lynch, J., Aye, T., & Ashraf, A. (2020, June). Perspectives of Pediatric Endocrinologists on Career Choice and Strategies to Stimulate Interest in Pediatric Endocrinology Subspecialty Training. In HORMONE RESEARCH IN PAEDIATRICS (Vol. 93, No. SUPPL 1, pp. 141-142). PMID: 34132198

Allen N, Desai N, Song C, Yu J, Prasad U & Francis G. Clinical features may help to identify children and adolescents with greatest risk for thyroid nodules. J Endocrinol Invest July 2020. 43(7):925-934. PMID: 31927747

Allen N, N Desai, C Song, J Yu, U Prasad, G Francis Clinical Features May Help to Identify Children and Adolescents With Greatest Risk for Thyroid Nodules. J Endocrinol 2020 Jul;43(7):925-934. Doi: 10.1007/s40618-019-01176-6. Epub 2020 Jan 11. PMID: 31927747

Lynch JL, Barrientos-Pérez M, Hafez M, Jalaludin MY, Kovarenko M, Rao PV, Weghuber D. Country-Specific Prevalence and Incidence of Youth-Onset Type 2 Diabetes: A Narrative Literature Review. Ann Nutr Metab. 2020;76(5):289-296. doi: 10.1159/000510499. Epub 2020 Sep 25. PMID: 32980841.

Tryggestad JB, Shah RD, Braffett BH, Bacha F, Gidding SS, Gubitosi-Klug RA, Shah AS, Urbina EM, Levitt Katz LE; TODAY Study Group. Circulating adhesion molecules and associations with HbA1c, hypertension, nephropathy, and retinopathy in the Treatment Options for type 2 Diabetes in Adolescent and Youth study. Pediatr Diabetes. 2020 Sep;21(6):923-931. doi: 10.1111/pedi.13062. Epub 2020 Jul 2. PMID: 32501612

Endocrine Conditions in Pediatrics. Ambreen Sonawalla, Rabab Jafri: Type 1 Diabetes. Published September 2020. pp 307-311 i. Ilet Function in Youth with Cystic Fibrosis with and without Liver Disease

Lopez-Alvarenga JC, Chittoor G, Paul SFD, Puppala S, Farook VS, Fowler SP, Resendez RG, Hernandez-Ruiz J, Diaz-Badillo A, Salazar D, Garza DD, Lehman DM, Mummidi S, Arya R, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R. Acanthosis nigricans as a composite marker of cardiometabolic risk and its complex association with obesity and insulin resistance in Mexican American children. PLoS One. 2020 Oct 15;15(10):e0240467. doi: 10.1371/journal.pone.0240467. PMID: 33057385

Health Care Coverage and Glycemic Control in Young Adults With Youth-Onset Type 2 Diabetes: Results From the TODAY2 Study. Diabetes Care. 2020 Oct;43(10):2469-2477. doi: 10.2337/dc20-0760. Epub 2020 Aug 10. PMID: 32778555

T Quattrin, MJ Haller, AK Steck, EI Felner, Y Li, Y Xia, JH Leu, R Zoka, JA Hedrick, MR Rigby, F Vercruysse, T1GER Study Investigators Collaborators. L Akright, S Aronoff, B Bode, L Chuck, L DiMeglio, E Felner, D Flynn, J Gaglia, S Gitelman, M Gottschalk, C Greenbaum, M Haller, K Herold, D Hsia, G Kletter, S Leichter, W Miers, L Philipson, G Prakasam, M Rayas, T Quattrin, B Reiner, A Steck, M Thompson, D Weiss, S Willi, K Wintergerst. Golimumab and Beta-Cell Function in Youth with New-Onset Type 1 Diabetes. N Engl J Med 2020 Nov 383(21):2007-2017. PMID: 33207093

Sandhu S, Orsi C, Francis GL, Wang Z, Fernandez R, Alkhouri N. Shear wave elastography reveals a high prevalence of liver fibrosis in overweight or obese Hispanic youth. J Ultrason. 2020 Nov;20(82):e162-e168. doi: 10.15557/JoU.2020.0027. PMID: 33365151

Srinivas, Mummidi, Vidya S. Farook, Reddivari Lavanya, Joselin Hernandez-Ruiz, Alvaro Diaz-Badillo, Sharon P. Fowler, Roy G. Resendez et al. “Serum carotenoids and Pediatric Metabolic Index predict insulin sensitivity in Mexican American children.” Scientific Reports (Nature Publisher Group) 11, no. 1. PMID: 33441626

Christison- Lagay ER, Baertschiger RM, Dinauer C, Francis GL, Malek MM, Lautz TB, Aldrink JH, Grant C, Rhee DS, Ehrlich P, Dasgupta R, Abdessalam S; APSA Cancer Committee. Pediatric differentiated thyroid carcinoma: An update from the APSA Cancer Committee. J Pediatr Surg. 2020 Nov;55(11):2273-2283. doi: 10.1016/j.jpedsurg.2020.05.003. Epub 2020 May 11. PMID: 32553450.