Advances in pediatric research have improved the lives of infants, children, adolescents, and society at large.  We are on the edge of exciting discoveries and initiatives to improve the lives of children and the adults they will become. We feel that the inclusion of children and adolescents in clinical research is essential to ensure that these individuals benefit from important scientific discoveries. Furthermore, studying child health across the stages of development is critical for understanding the pathophysiology of disease and is the basis for developing preventive and curative treatments for all.