Clinical Trials

Clinical trials are part of clinical research and are at the heart of all medical discoveries. Your voluntary participation in a clinical trial may lead to new and better treatment for kidney disease in near future.

Nephrologists (kidney doctors) at UT Health San Antonio conduct clinical research trials. To learn more about how you can participate in one of the following clinical research trials, please call at 210-358-7447:

Current clinical trials with open enrollment:

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease (FIDELIO-DKD)

This study evaluates whether a new medicine (finerenone), in addition to current standard treatment, is effective and safe in treating kidney disease in patients with type 2 diabetes mellitus, when compared to a placebo.

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Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease (FIGARO-DKD)

This study evaluates whether a new medicine (finerenone), in addition to current standard treatment, is effective and safe in treating kidney disease in patients with type 2 diabetes mellitus, when compared to a placebo.

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Transformative Research in Diabetic Nephropathy (TRIDENT)

This study, a unique public-private initiative, aims to develop ground-breaking treatment for diabetic kidney disease.

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Upcoming clinical trials:

Empa Kidney

This study will assess the benefits of an approved new medication (SGLT2 inhibitor) on cardiac (heart) and kidney disease progression and outcomes in patients with chronic kidney disease.

Precision Clinical Trial for Pirfenidone in Kidney Disease

This is a new innovative clinical trial testing an oral blocker of kidney scarring and using novel technologies to identify the right dose for the right patient. This work has developed out of research from our own faculty and will serve as a model for clinical trials in the future.

A new medicine for itching in chronic kidney disease patients

The objective is to evaluate the safety and effectiveness of an investigational medicine in reducing the intensity of itch in chronic kidney disease patients with moderate-to-severe itching

A new medicine for itching in hemodialysis patients

The objective is to evaluate the safety and effectiveness of an investigational medicine in reducing the intensity of itch in hemodialysis patients with moderate-to-severe itching.